1700120B22Rik Inhibitors
1700120B22Rik inhibitors represent a class of chemical compounds that can be utilized as valuable tools in molecular and cellular research to investigate the role and functions of the protein encoded by the gene 1700120B22Rik. These inhibitors are developed to serve as essential instruments for probing the biochemical and cellular processes associated with this specific protein. Researchers employ these compounds with the aim of modulating the protein's activity in controlled laboratory settings, enabling a deeper understanding of its functions and interactions within the cellular context.
These inhibitors can be grouped based on their various mechanisms of action, targeting specific signaling pathways or cellular processes that may involve 1700120B22Rik. For instance, some inhibitors may work by disrupting key kinases in crucial pathways, thereby indirectly impacting the protein's function by altering downstream signaling events. Others may influence epigenetic modifications or chromatin structure, potentially affecting gene expression and indirectly influencing the protein's role in cellular processes. These inhibitors enable scientists to investigate how changes in the activity of 1700120B22Rik affect cellular responses, protein-protein interactions, and gene regulation. By employing a diverse range of chemical compounds, researchers can gain valuable insights into the intricate biology of 1700120B22Rik and its contributions to cellular functions without necessarily considering their utility beyond the realm of scientific inquiry.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is a well-known inhibitor that targets mTOR (mechanistic target of rapamycin), a central regulator of cell growth and proliferation. By binding to mTOR, rapamycin disrupts its kinase activity, specifically inhibiting the mTORC1 complex. This disruption can lead to the downregulation of processes like protein synthesis and cell cycle progression, indirectly affecting the function of proteins within the cell. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent inhibitor that affects cell growth and survival signaling pathways by targeting phosphoinositide 3-kinase (PI3K). It covalently binds to the active site of PI3K, impairing its function and disrupting downstream signaling cascades. This interference with PI3K-mediated signaling can indirectly influence cellular responses and protein interactions. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor. It achieves its inhibitory effects by competing with ATP for binding to the catalytic domain of protein kinases. As a result, staurosporine can affect multiple signaling pathways and cellular processes by suppressing the phosphorylation of various target proteins, indirectly impacting cellular functions. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is another inhibitor that targets PI3K, influencing various signaling pathways. By blocking PI3K activity, LY294002 disrupts downstream events related to cell growth, proliferation, and survival. This indirect modulation of cellular processes can affect the interactions and functions of numerous proteins within the cell. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAP kinase, which plays a role in stress responses. This compound binds to the ATP-binding pocket of p38 MAP kinase, inhibiting its activation. The downstream consequences include the modulation of protein interactions and signaling pathways related to stress responses and inflammation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK (mitogen-activated protein kinase kinase), an upstream activator of ERK (extracellular signal-regulated kinase) in the MAPK pathway. By blocking MEK activity, PD98059 indirectly influences ERK phosphorylation and downstream signaling events, potentially impacting protein functions and cellular responses. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK (c-Jun N-terminal kinase), which influences apoptosis and cellular differentiation. This compound competes with ATP for binding to JNK, inhibiting its kinase activity. By doing so, SP600125 can indirectly affect cellular processes, protein interactions, and gene expression related to JNK signaling. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine acts on DNA methylation, impacting gene expression. It incorporates into DNA during replication, leading to DNA demethylation. This alteration in DNA methylation patterns can indirectly influence the expression of genes and proteins associated with various cellular functions and pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor, affecting chromatin structure and gene expression. By inhibiting histone deacetylases, it leads to histone hyperacetylation, altering chromatin accessibility and gene transcription. This indirect modulation can influence the expression of proteins and cellular processes governed by gene regulation. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Cyclopamine is known for its inhibition of the Hedgehog signaling pathway. It targets the Smoothened protein, disrupting downstream Hedgehog signaling events. As a result, Cyclopamine can indirectly affect cellular responses and protein interactions related to Hedgehog pathway-controlled processes. | ||||||