POLR2G Antibody (G-9): sc-393890

POLR2G Antibody (G-9) is a mouse monoclonal IgG2a antibody that detects POLR2G in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POLR2G, also known as RPB7, hRPB19, or hsRPB7, is the seventh largest subunit of RNA polymerase II, a crucial enzyme responsible for the transcription of protein-coding genes. POLR2G plays a vital role in transcription initiation by forming a subcomplex with the RPB4 subunit, which is essential for proper RNA polymerase II complex function. The interaction between POLR2G and RPB4 helps maintain polymerase structural integrity and prevents double-stranded DNA from entering the active site in its closed conformation, ensuring accurate transcription initiation. POLR2G′s coordination with other subunits and transcription factors highlights POLR2G′s importance in regulating gene expression, making POLR2G a key player in cellular processes and a valuable target for research in gene regulation and transcriptional control. Anti-POLR2G antibody (G-9) is an indispensable tool for researchers studying transcription mechanisms and RNA polymerase II′s role in various biological contexts.

The preferred POLR2G antibody is POLR2G Antibody (C-2): sc-398213.