Date published: 2026-4-21

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POLR3B Antibodies

Santa Cruz Biotechnology delivers a wide array of POLR3B monoclonal antibodies for investigating RNA polymerase III function and regulation. POLR3B monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). POLR3B, a subunit of RNA polymerase III, plays a crucial role in the transcription of small RNAs, including tRNAs and 5S rRNA, which are essential for protein synthesis and cellular function. Proper POLR3B activity maintains cellular homeostasis and stress response mechanisms. Research has shown that POLR3B dysregulation is linked to various pathological conditions, highlighting its significance in human health and disease. Understanding POLR3B function and regulation can provide valuable insights into RNA polymerase III-mediated transcription and its impact on cellular processes. Investigating POLR3B expression patterns helps reveal its role in different tissue types and developmental stages. POLR3B research continues to uncover new aspects of RNA polymerase III biology and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of POLR3B and its impact on human health.

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POLR3B Antibodies

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POLR3B Antibody (G-6)

sc-515362mouse IgG1 κ92-111 (h)WB, IP, IF, ELISAm, r, h
3
(1)

POLR3B CRISPR Knockout, HDR and Double Nickase Plasmids

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POLR3B CRISPR/Cas9 KO Plasmid (h)

sc-406739hGene KnockoutGFP0
(0)

POLR3B siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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POLR3B siRNA (h)

sc-95786hGene SilencingN/A0
(0)

POLR3B shRNA Plasmid (h)

sc-95786-SHhGene SilencingPuromycin0
(0)

POLR3B shRNA (h) Lentiviral Particles

sc-95786-VhGene SilencingPuromycin0
(0)

POLR3B siRNA (m)

sc-152377mGene SilencingN/A0
(0)

POLR3B shRNA Plasmid (m)

sc-152377-SHmGene SilencingPuromycin0
(0)

POLR3B shRNA (m) Lentiviral Particles

sc-152377-VmGene SilencingPuromycin0
(0)