Date published: 2025-10-12

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POLR2I Antibodies

Santa Cruz Biotechnology delivers a wide array of POLR2I monoclonal antibodies for investigating RNA polymerase II in transcription regulation. POLR2I monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). POLR2I, also known as the second largest subunit of RNA polymerase II, plays a critical role in synthesizing messenger RNA (mRNA) and is essential for the transcription of protein-coding genes. RNA polymerase II function is vital for cellular processes such as gene expression regulation, cell differentiation, and response to environmental signals. POLR2I activity has been extensively studied in various diseases, including cancer, highlighting its importance in cellular homeostasis. Researchers can utilize POLR2I monoclonal antibodies to explore transcription mechanisms in both normal and pathological conditions. Understanding POLR2I function contributes to knowledge about fundamental cellular processes and disease development. POLR2I research continues to reveal new insights into gene regulation and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support the scientific community by enabling precise investigation of POLR2I's role in transcription and disease mechanisms.

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POLR2I Antibodies

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POLR2I Antibody (F-11)

sc-398049mouse IgG1 κ1-120 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(1)

POLR2I CRISPR Knockout, HDR and Double Nickase Plasmids

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POLR2I CRISPR/Cas9 KO Plasmid (h)

sc-410948hGene KnockoutGFP0
(0)

POLR2I HDR Plasmid (h)

sc-410948-HDRhHomology Directed RepairPuromycin0
(0)

POLR2I Double Nickase Plasmid (h)

sc-410948-NIChGene KnockoutPuromycin0
(0)

POLR2I Double Nickase Plasmid (h2)

sc-410948-NIC-2hGene KnockoutPuromycin0
(0)

POLR2I CRISPR/Cas9 KO Plasmid (m)

sc-427575mGene KnockoutGFP0
(0)

POLR2I HDR Plasmid (m)

sc-427575-HDRmHomology Directed RepairPuromycin0
(0)

POLR2I Double Nickase Plasmid (m)

sc-427575-NICmGene KnockoutPuromycin0
(0)

POLR2I Double Nickase Plasmid (m2)

sc-427575-NIC-2mGene KnockoutPuromycin0
(0)

POLR2I CRISPR Activation Products

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POLR2I CRISPR Activation Plasmid (h)

sc-410948-ACThGene ActivationPuro, Blast, Hygro0
(0)

POLR2I CRISPR Activation Plasmid (h2)

sc-410948-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

POLR2I Lentiviral Activation Particles (h)

sc-410948-LAChGene ActivationPuro, Blast, Hygro0
(0)

POLR2I Lentiviral Activation Particles (h2)

sc-410948-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

POLR2I CRISPR Activation Plasmid (m)

sc-427575-ACTmGene ActivationPuro, Blast, Hygro0
(0)

POLR2I CRISPR Activation Plasmid (m2)

sc-427575-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

POLR2I Lentiviral Activation Particles (m)

sc-427575-LACmGene ActivationPuro, Blast, Hygro0
(0)

POLR2I Lentiviral Activation Particles (m2)

sc-427575-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

POLR2I siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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POLR2I siRNA (h)

sc-97881hGene SilencingN/A0
(0)

POLR2I shRNA Plasmid (h)

sc-97881-SHhGene SilencingPuromycin0
(0)

POLR2I shRNA (h) Lentiviral Particles

sc-97881-VhGene SilencingPuromycin0
(0)

POLR2I siRNA (m)

sc-152373mGene SilencingN/A0
(0)

POLR2I shRNA Plasmid (m)

sc-152373-SHmGene SilencingPuromycin0
(0)

POLR2I shRNA (m) Lentiviral Particles

sc-152373-VmGene SilencingPuromycin0
(0)