Date published: 2026-4-12

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POLR2E Antibody (C-10): sc-390902

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Datasheets
  • POLR2E Antibody (C-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 7-210 representing full length of POLR2E of human origin
  • recommended for detection of POLR2E of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for POLR2E Antibody (C-10) for WB applications. These reagents are now offered in bundles with POLR2E Antibody (C-10) (see ordering information below).
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    POLR2E Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects POLR2E in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POLR2E, also known as polymerase (RNA) II (DNA directed) polypeptide E, RPB5, XAP4, RPABC1, hRPB25, or hsRPB5, is a crucial 210 amino acid nuclear protein that plays a vital role in transcription by forming part of the multi-subunit RNA polymerase II complex. This complex is essential for synthesizing messenger RNA and various non-coding RNAs, which are critical for gene expression regulation and cellular function. POLR2E′s interaction with TFIIF RAP 30 is particularly significant, as this interaction facilitates the association between RNA polymerase II and TFIIF, thereby enhancing transcriptional efficiency and accuracy. Understanding POLR2E′s function and interactions is important for elucidating transcription regulation mechanisms and their implications in various biological processes and diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    POLR2E Antibody (C-10)

    sc-390902
    200 µg/ml
    $322.00

    POLR2E Antibody (C-10): m-IgG Fc BP-HRP Bundle

    sc-540868
    200 µg Ab; 10 µg BP
    $361.00

    POLR2E Antibody (C-10): m-IgG1 BP-HRP Bundle

    sc-542430
    200 µg Ab; 20 µg BP
    $361.00

    POLR2E (C-10) Neutralizing Peptide

    sc-390902 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-390902 P appropriate for?

    Asked by: cjMara
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of POLR2EProduced positive Western blot data of POLR2E expression in MCF7, Hep G2 and A549 whole cell lysates. -SCBT QC
    Date published: 2014-09-11
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    POLR2E Antibody (C-10) is rated 5.0 out of 5 by 1.
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