MMP-2/MMP-3 Inhibitor II MF: C21H23N7O2S2
MW: 469.6
An MMP-2 and -3 type matrix metalloproteinase inhibitor.

MMP-2/MMP-3 Inhibitor II

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Application: MMP-2/MMP-3 Inhibitor II is an MMP-2 and -3 type matrix metalloproteinase inhibitor
Molecular Weight: 469.6
Molecular Formula: C21H23N7O2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

MMP-2/MMP-3 Inhibitor II is a potent inhibitor of MMP-2 (Ki = 1.5 µM) and MMP-3 (Ki = 520 nM). The family of MMPs (matrix metalloproteinases) are commonly known to be involved in the degradation of various extracellular matrix proteins.


References

1. Jacobsen, E J., et al., 1999. Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors. Journal of medicinal chemistry. 42(9): 1525-36. PMID: 10229623

Physical State :
Solid
Solubility :
DMSO
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3728863
SMILES :
C1CN(CCN1C2=CC=CC=N2)C(=O)C(CC3=CC=CC=C3)NC(=O)NC4=NNC(=S)S4

Download SDS (MSDS)

Certificate of Analysis

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