caspase-9 Antibody (9CSP02): sc-81589

caspase-9 Antibody (9CSP02) is a mouse monoclonal IgG1 antibody that detects caspase-9 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Caspase-9 plays a pivotal role in the intrinsic pathway of apoptosis, acting as an initiator caspase that is activated in response to cellular stress and damage. Upon activation, caspase-9 cleaves and activates downstream effector caspases, such as caspase-3 and caspase-7, leading to the execution phase of apoptosis. This process is crucial for maintaining cellular homeostasis and eliminating damaged or unwanted cells, thereby preventing the development of various diseases, including cancer. The activation of caspase-9 is tightly regulated and can be influenced by various factors, including post-translational modifications such as phosphorylation and ubiquitination, which can affect activity and stability. Anti-caspase-9 antibody (9CSP02) enables researchers to gain valuable insights into the mechanisms of apoptosis and the role of caspase-9 in disease progression, making this tool essential for studies in cell biology and therapeutic development.

The preferred caspase-9 antibody is caspase-9 Antibody (96.1.23): sc-56076.