Date published: 2025-9-9

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Peg10 억제제

Peg10 Inhibitors refer to a diverse class of chemical compounds designed to target and modulate the activity of the PEG10 gene, primarily by interfering with its expression or function. PEG10, which stands for Paternally Expressed Gene 10, is a unique imprinted gene in mammals, implicated in various cellular processes, including cell proliferation, apoptosis, and cancer development. Inhibitors within this class act as valuable tools for researchers and scientists to investigate the intricate mechanisms through which PEG10 influences these processes. These compounds exhibit diverse chemical structures and mechanisms of action, enabling a comprehensive exploration of PEG10's roles in cellular biology.

The mechanisms by which Peg10 Inhibitors function can vary widely. Some compounds focus on epigenetic regulation, impacting PEG10 gene expression by targeting DNA methylation or histone modifications within its regulatory regions. Others may affect post-transcriptional processing, mRNA stability, or translation of PEG10 transcripts. Additionally, Peg10 Inhibitors can potentially interfere with the interactions between PEG10 and its downstream targets, inhibiting specific cellular pathways or signaling cascades associated with PEG10 function. By providing a suite of chemical tools to manipulate PEG10, this class of inhibitors empowers researchers to unravel the complex web of molecular events associated with PEG10's role in normal cellular physiology and disease states. Understanding the mechanisms and consequences of PEG10 inhibition can pave the way for new insights into the fundamental biology of this gene and its potential implications in various biological contexts.

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제품명CAS #카탈로그 번호 수량가격引用RATING

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

제뷸린은 PEG10 프로모터 영역의 메틸화를 방지하여 PEG10 유전자 발현을 감소시키는 DNA 메틸전달효소 억제제입니다.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

데시타빈이라고도 알려진 이 억제제는 DNA 메틸 전이 효소를 억제하고 PEG10 프로모터를 탈메틸화하여 제불린과 유사하게 작용합니다.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108은 PEG10 프로모터 메틸화에 관여하는 것을 포함하여 DNA 메틸전달효소의 저분자 억제제입니다.

Scriptaid

287383-59-9sc-202807
sc-202807A
1 mg
5 mg
$63.00
$179.00
11
(2)

스크립타이드는 히스톤 탈아세틸화 효소(HDAC) 억제제로 후성유전학적 조절을 조절하여 PEG10 발현에 간접적으로 영향을 미칩니다.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

이 사이티딘 유사체는 DNA에 통합되어 DNA 메틸전달효소를 억제하여 PEG10 프로모터 메틸화에 영향을 미칩니다.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

발프로산은 히스톤 아세틸화 패턴을 변경하여 PEG10 발현에 영향을 줄 수 있는 HDAC 억제제입니다.

UNC0638

1255580-76-7sc-397012
10 mg
$315.00
(0)

UNC0638은 히스톤 메틸화 변화를 통해 PEG10 발현에 간접적으로 영향을 미치는 G9a 히스톤 메틸화 전이효소 억제제입니다.

EPZ6438

1403254-99-8sc-507456
1 mg
$66.00
(0)

EPZ-6438은 히스톤 메틸화 패턴에 영향을 미쳐 PEG10 발현을 조절하는 EZH2 히스톤 메틸화 전이 효소 억제제입니다.