IL-20 Inhibitors
IL-20 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of Interleukin-20 (IL-20), a cytokine that plays a role in regulating immune responses and inflammation. Interleukin-20 is part of the IL-10 cytokine family and is produced by various immune cells, including macrophages and monocytes. It is involved in both innate and adaptive immune responses and has been implicated in inflammatory conditions, autoimmune diseases, and tissue repair processes. Inhibitors of IL-20 are developed to interact with this cytokine, interfering with its signaling pathways and modulating the immune and inflammatory responses associated with IL-20 activity.
IL-20 inhibitors are typically designed as antibodies, small molecules, or peptides that can bind to IL-20, thereby blocking its interactions with its receptors on target cells. By doing so, these inhibitors may disrupt the downstream signaling cascades activated by IL-20, influencing cellular responses such as cytokine production, cell migration, and tissue repair processes. Research into IL-20 inhibitors is essential for elucidating the role of IL-20 in immune regulation and inflammation and for exploring strategies to modulate these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is known to modulate inflammatory pathways and may downregulate cytokine expression, including IL-20, through its effects on transcription factor activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to interfere with the NF-kB pathway, potentially decreasing pro-inflammatory cytokine expression like IL-20. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $114.00 $525.00 | 4 | |
Indirubin may inhibit cyclin-dependent kinases and disrupt cell cycle progression, which can indirectly reduce cytokine expression such as IL-20. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, is known to modulate signal transduction pathways and may reduce the expression of various cytokines, including IL-20. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, the main catechin in green tea, may inhibit inflammatory responses and potentially downregulate the expression of IL-20. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane can affect the NF-kB pathway and potentially modulate the expression of proteins like IL-20. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
Bay 11-7082 is an inhibitor of NF-kB activation, which may lead to reduced transcription of NF-kB responsive genes, including IL-20. | ||||||
Wogonin, S. baicalensis | 632-85-9 | sc-203313 | 10 mg | $200.00 | 8 | |
Wogonin is reported to have anti-inflammatory effects which might include the downregulation of cytokines such as IL-20. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
CAPE is an inhibitor of NF-kB and might reduce the expression of IL-20 through this pathway. | ||||||
Andrographolide | 5508-58-7 | sc-205594 sc-205594A | 50 mg 100 mg | $15.00 $40.00 | 7 | |
Andrographolide has been shown to attenuate expression of inflammatory cytokines and could potentially affect IL-20 levels. | ||||||