TES Activators
TES Activators refers to a class of chemical compounds and molecules that have the capability to specifically activate or modulate the activity of the TES protein (Testin LIM Domain Protein). TES, a member of the LIM domain protein family, plays a pivotal role in regulating several crucial cellular processes, including cytoskeletal organization, cell adhesion, and cell motility. Therefore, the identification and study of TES activators are of significant interest in cell biology and molecular research.
TES activators encompass a diverse range of compounds, including small molecules, peptides, and biological agents, that are known to interact directly or indirectly with TES and enhance its functionality. These compounds typically operate through various mechanisms, such as promoting TES-mediated signal transduction, enhancing protein-protein interactions, or influencing key signaling pathways that converge on TES regulation. Researchers have investigated these activators to gain insights into the intricate roles of TES within the cellular context and to understand the underlying molecular mechanisms that govern its function.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Indirectly activates TES by triggering PI3K, which activates TES and influences cytoskeletal dynamics. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Indirectly activates TES by inhibiting ROCK, a downstream activator of TES-mediated cytoskeletal organization. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Indirectly activates TES through the activation of PKC, which activates TES in specific signaling pathways. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Indirectly stimulates TES by inhibiting PKC, an activator of TES in various cellular contexts. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $245.00 | 9 | |
Indirectly activates TES by activating PKC, which may interact with TES in specific signaling pathways. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Activates TES indirectly by inhibiting actin polymerization, which activates TES through the disruption of actin filaments, a key component of TES-regulated cytoskeletal organization. | ||||||
GGTI 298 | 1217457-86-7 | sc-361184 sc-361184A | 1 mg 5 mg | $193.00 $838.00 | 2 | |
Indirectly activates TES by inhibiting geranylgeranylation of small GTPases, thus activating their downstream signaling pathways that interact with TES. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Activates TES by inhibiting specific tyrosine kinases involved in signaling pathways where TES plays a role. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Indirectly activates TES by activating adenylyl cyclase, increasing cAMP levels, which can activate TES-regulated cellular processes. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Indirectly activates TES by inhibiting cAMP phosphodiesterase, resulting in increased cAMP levels that activate TES-associated pathways. | ||||||