Date published: 2026-4-24

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SLURP-2 Activators

The chemical class known as SLURP-2 activators comprises a diverse group of compounds that can influence the activity of the protein Secreted LY6/PLAUR Domain Containing 2 (SLURP-2), which is a member of the Ly6/uPAR family of proteins. These compounds can engage various cellular mechanisms and pathways that, in turn, can modulate the function of SLURP-2. The activation can occur through direct interaction with the protein or, more commonly, by indirect effects on the cellular environment and signaling cascades that SLURP-2 is a part of. The chemicals in this class can affect cholinergic signaling, immune responses, and cellular processes such as adhesion and migration.

Each member of the SLURP-2 activators class can interact with different molecular targets and signaling pathways that are known to be involved in processes where SLURP-2 is presumed to play a role. These interactions can upregulate the expression of SLURP-2 or modulate its activity by altering the cellular context. For instance, some activators can enhance the signaling of certain neurotransmitters, which can lead to a cascade of intracellular events that can influence SLURP-2 activity. Others can affect gene expression patterns that can lead to increased production of SLURP-2. Additionally, some can modulate immune responses, potentially affecting the release or action of SLURP-2 in the context of inflammation or immune cell signaling. Importantly, the actions of these activators are not isolated to SLURP-2 and can have broad effects, influencing a variety of cellular functions and pathways. The chemical class of SLURP-2 activators represents a complex and multifaceted group of compounds that can play a role in modulating the activity of the SLURP-2 protein through various biological mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pilocarpine

92-13-7sc-479256
100 mg
$255.00
1
(0)

Muscarinic receptor agonist, could possibly activate SLURP2 by modulating parasympathetic outflow and associated pathways.

Galanthamine

357-70-0sc-218556
10 mg
$320.00
(0)

Allosteric modulator of nicotinic acetylcholine receptors, could possibly activate the effect of SLURP2 on cholinergic neurons.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Signaling molecule that regulates gene expression and could possibly activate SLURP2 expression as part of skin homeostasis.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Involved in immune regulation and could possibly activate SLURP2 expression or activity within immune pathways.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Polyphenol with anti-inflammatory properties, could possibly activate immune pathways that involve SLURP2.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

Main component of green tea with anti-inflammatory effects, could possibly activate immune pathways and affect SLURP2.

IBMX

28822-58-4sc-201188
sc-201188B
sc-201188A
200 mg
500 mg
1 g
$260.00
$350.00
$500.00
34
(1)

Non-selective inhibitor of phosphodiesterases, may increase cAMP levels and could possibly activate pathways involving SLURP2.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Phosphodiesterase inhibitor, can increase cAMP levels and could possibly activate SLURP2-related pathways.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), can increase cytosolic calcium levels, which could possibly activate SLURP2 if it is regulated by intracellular calcium.