OTTMUSG00000019138 Activators
The protein "ovary testis transcribed" (Gm10439) represents a significant but not fully understood component in the biological system, likely playing a role in reproductive biology. The specific function of this protein is yet to be characterized, reflecting a common challenge in molecular biology - determining the roles and mechanisms of less studied or uncharacterized proteins. Comprehensive studies including biochemical assays and in vivo models are necessary to elucidate the interactions, effects, and precise functions of this protein within the cellular context.
The activation of Gm10439, based on the listed activators, suggests involvement in various cellular processes governed by cyclic AMP (cAMP), protein kinase A (PKA), and other secondary messengers. These pathways are critical in regulating cellular activities like cell proliferation, apoptosis, or differentiation, which could be particularly relevant in the context of gonadal development and function. The activators proposed, selected based on their roles in these pathways, provide a theoretical basis for future research into the protein's function. Investigating Gm10439's role within these signaling networks is vital for a comprehensive understanding of its biological role and regulation. This exploration is not only crucial for elucidating the specific functions of Gm10439 but also contributes to the broader understanding of cellular signaling mechanisms, particularly in reproductive biology. The activation of Gm10439 by these chemicals, while currently speculative, highlights the need for targeted research to unravel its exact role and significance in biological systems.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine, through adrenergic receptors, increases cAMP via adenylate cyclase activation. Elevated cAMP might lead to PKA activation, potentially phosphorylating and activating ovary testis transcribed protein, implicating it in adrenergic signaling. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterases, raising cAMP levels. This increase can activate PKA, potentially leading to phosphorylation and activation of ovary testis transcribed protein, linking it to cAMP-mediated cellular responses. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates EP receptors, enhancing adenylate cyclase activity and cAMP levels. Elevated cAMP may activate PKA, potentially phosphorylating and activating ovary testis transcribed protein, indicating a role in prostaglandin-mediated signaling. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a phosphodiesterase inhibitor, increases cAMP levels, potentially enhancing PKA activity. This may facilitate phosphorylation and activation of ovary testis transcribed protein, suggesting a role in metabolic and stress response pathways. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram, a PDE4 inhibitor, elevates cAMP levels, potentially leading to PKA activation. PKA may phosphorylate and activate ovary testis transcribed protein, implying its role in cognitive and inflammatory pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin activates stress-activated protein kinases, potentially influencing ovary testis transcribed protein activity through stress response signaling pathways. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $105.00 $250.00 | 8 | |
Zaprinast inhibits PDE5, raising cGMP levels, potentially enhancing cAMP pathways and leading to PKA activation and phosphorylation of ovary testis transcribed protein, suggesting a role in vascular functions. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
dbcAMP, a cAMP analog, directly activates PKA, potentially leading to phosphorylation and activation of ovary testis transcribed protein, emphasizing its role in cAMP-dependent signaling mechanisms. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $165.00 $697.00 | 7 | |
Milrinone inhibits PDE3, increasing cAMP levels, potentially leading to PKA activation. This might result in phosphorylation and activation of ovary testis transcribed protein, suggesting a role in cardiac function. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, raises cAMP levels, potentially leading to PKA activation and phosphorylation of ovary testis transcribed protein, indicating its involvement in metabolic regulation. | ||||||