FAM136B Activators are a niche category within the expansive field of chemical agents, pertaining specifically to the modulation of the FAM136B protein. This protein, encoded by the FAM136B gene, is a part of a larger family of proteins that have diverse roles in cellular processes. The activators themselves are compounds that interact with the FAM136B protein to enhance its biological activity. The precise function of FAM136B within cells is not fully elucidated, but proteins in this family typically participate in fundamental cellular operations such as signaling, structural integrity, and the regulation of gene expression. Thus, compounds that activate FAM136B are thought to influence these underlying cellular functions through their interaction with the protein.
The chemical structure of FAM136B Activators can vary widely, but they share the common characteristic of being able to bind to the FAM136B protein and modulate its activity. This interaction often involves a high degree of specificity, with the activators exhibiting a preference for the FAM136B protein over other proteins. The binding of these activators to the FAM136B protein may induce a conformational change in the protein structure, which, in turn, could alter the protein's activity. This mode of action is typical of many protein activators and is reliant on the precise alignment and interaction of the activator's molecular structure with specific sites on the protein. The specificity and efficacy of FAM136B Activators depend on the ability of their molecular architecture to fit and engage with the protein's active site or allosteric sites, thereby facilitating an increase in its intrinsic activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which regulates numerous cellular functions and might influence FAM136B activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Calcium ionophore that increases intracellular calcium levels. Calcium signaling can play a role in activating numerous proteins including potential interaction with FAM136B. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibitor of PI3K, a kinase involved in multiple cellular pathways. By modulating PI3K activity, it can influence downstream proteins including FAM136B. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, a central regulator of cell growth and metabolism. This inhibition can shift cellular pathways potentially affecting FAM136B. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Another calcium ionophore which can increase intracellular calcium concentration, potentially influencing FAM136B activity through calcium-mediated pathways. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Analog of cAMP which can activate PKA, leading to phosphorylation and activation of multiple cellular proteins, potentially including FAM136B. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Inhibitor of protein phosphatases 1 and 2A, affecting phosphorylation state of proteins and can influence pathways involving FAM136B. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Activates the MAPK pathway by stressing cells. Through MAPK pathway modulation, it can potentially influence FAM136B. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Another MEK inhibitor that affects the MAPK pathway. By modulating this pathway, it may influence the activity of proteins such as FAM136B. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Inhibitor of tyrosine kinases which play a key role in various signaling pathways. By affecting these pathways, FAM136B activity can potentially be modulated. | ||||||