CTRP7 activators encompass a diverse group of compounds that indirectly increase the expression or activity of CTRP7 through various biochemical and cellular pathways. Agents such as forskolin and IBMX act on the cAMP signaling cascade, increasing CTRP7 expression by enhancing PKA activity, which is known to trigger transcriptional changes. The PPAR-gamma agonists, rosiglitazone and pioglitazone, engage nuclear receptors that modulate the expression of numerous genes, including those involved in adipokine production, and could thereby increase levels of CTRP7. Metformin and AICAR, through their action on the AMPK signaling pathway, are known to influence metabolic regulation, which might lead to upregulated CTRP7 expression, considering the protein's involvement in metabolic processes.
Further, compounds such as L-arginine and sodium nitroprusside, which modulate nitric oxide synthesis and signaling, could also alter the expression of CTRP7, given the protein's role in vascular function. Meanwhile, resveratrol and curcumin, by modulating sirtuin and NF-kB pathways, respectively, may influence the expression of CTRP7 in relation to metabolic and inflammatory states. Vitamin D3, through its receptor, could impact CTRP7 expression due to the role of vitamin D in gene regulation. Lastly, omega-3 fatty acids, known for their anti-inflammatory effects, could modulate the expression of various adipokines, including CTRP7, as part of their influence on inflammation and metabolic health.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Adenylyl cyclase activator that increases cAMP levels, which may upregulate CTRP7 expression by enhancing the protein kinase A (PKA) signaling pathway, leading to transcriptional changes. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
Phosphodiesterase inhibitor that prevents cAMP degradation, possibly leading to enhanced PKA activity and subsequent upregulation of CTRP7 expression. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
PPAR-gamma agonist that regulates gene expression and might increase CTRP7 expression as PPAR-gamma can influence adipokine production. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Another PPAR-gamma agonist with a potential to increase CTRP7 expression by modulating adipokine production pathways. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
AMP-activated protein kinase (AMPK) activator that can affect transcriptional regulation and may increase the expression of CTRP7 through the AMPK signaling pathway. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AMPK agonist that can lead to transcriptional changes affecting CTRP7 expression through AMPK pathway activation. | ||||||
L-Arginine | 74-79-3 | sc-391657B sc-391657 sc-391657A sc-391657C sc-391657D | 5 g 25 g 100 g 500 g 1 kg | $20.00 $31.00 $61.00 $219.00 $352.00 | 2 | |
Nitric oxide precursor that could enhance the synthesis of nitric oxide, potentially influencing the expression of proteins involved in vascular homeostasis, including CTRP7. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Nitric oxide donor that may influence vasodilatory pathways, potentially affecting the expression of CTRP7 as a response to changes in vascular dynamics. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Sirtuin activator that can modulate metabolic pathways and has the potential to influence the expression of CTRP7 through sirtuin-mediated signaling. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulator of NF-kB signaling that may alter the transcription of inflammation-related proteins and could influence CTRP7 expression by modulating inflammatory responses. | ||||||