Date published: 2026-7-28

1-800-457-3801

SCBT Portrait Logo
Seach Input

Shank Antibodies

Santa Cruz Biotechnology provides a broad selection of Shank monoclonal antibodies for advanced research in neuroscience and cellular biology. Shank monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Shank proteins play a crucial role in the organization of synapses and are essential for proper neuronal signaling and communication. Shank proteins contribute to the regulation of synaptic strength and plasticity, which are fundamental processes for learning and memory. Dysregulation of Shank proteins has been implicated in several neurodevelopmental disorders, making Shank proteins significant targets for research aimed at understanding these conditions. Researchers can utilize Shank monoclonal antibodies to investigate synaptic organization and function in various experimental models. Understanding Shank protein expression patterns helps reveal their role in both normal brain development and pathological conditions. Shank monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance our understanding of neurological disorders and potential therapeutic approaches.

SEE ALSO...

Shank Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Shank 1 Antibody (E-1)

sc-398630mouse IgG1 κ1701-1830 (h)WB, IP, IF, ELISAm, r, h

new

(1)

Shank 1/2/3 Antibody (G-12)

sc-393963mouse IgG2a κ2124-2153 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(2)

Shank 2 Antibody (A-11)

sc-271834mouse IgG1 κ996-1110 (h)WB, IP, IF, ELISAm, r, h
2
(5)

Shank 2 Antibody (B-4)

sc-365121mouse IgG2b κ996-1110 (h)WB, IP, IF, ELISAm, r, h
1
(2)

Shank 3 Antibody (C-4)

sc-377088mouse IgG1 κ1431-1590 (h)WB, IP, IF, ELISAm, r, h
8
(5)

Shank 3 Antibody (E-1)

sc-377470mouse IgG2a κ1431-1590 (h)WB, IP, IF, ELISAm, r, h
3
(4)

Shank siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Shank 1 siRNA (h)

sc-42196hGene SilencingN/A0
(0)

Shank 1 shRNA Plasmid (h)

sc-42196-SHhGene SilencingPuromycin0
(0)

Shank 1 shRNA (h) Lentiviral Particles

sc-42196-VhGene SilencingPuromycin0
(0)

Shank 1 siRNA (m)

sc-42197mGene SilencingN/A
1
(0)

Shank 1 shRNA Plasmid (m)

sc-42197-SHmGene SilencingPuromycin
1
(0)

Shank 1 shRNA (m) Lentiviral Particles

sc-42197-VmGene SilencingPuromycin
1
(0)

Shank 2 siRNA (h)

sc-42198hGene SilencingN/A0
(0)

Shank 2 shRNA Plasmid (h)

sc-42198-SHhGene SilencingPuromycin0
(0)

Shank 2 shRNA (h) Lentiviral Particles

sc-42198-VhGene SilencingPuromycin0
(0)

Shank 2 siRNA (m)

sc-42199mGene SilencingN/A0
(0)

Shank 2 shRNA Plasmid (m)

sc-42199-SHmGene SilencingPuromycin0
(0)

Shank 2 shRNA (m) Lentiviral Particles

sc-42199-VmGene SilencingPuromycin0
(0)

Shank 3 siRNA (h)

sc-42200hGene SilencingN/A0
(0)

Shank 3 shRNA Plasmid (h)

sc-42200-SHhGene SilencingPuromycin0
(0)

Shank 3 shRNA (h) Lentiviral Particles

sc-42200-VhGene SilencingPuromycin0
(0)

Shank 3 siRNA (m)

sc-42201mGene SilencingN/A0
(0)

Shank 3 shRNA Plasmid (m)

sc-42201-SHmGene SilencingPuromycin0
(0)

Shank 3 shRNA (m) Lentiviral Particles

sc-42201-VmGene SilencingPuromycin0
(0)

Shank 3 siRNA (r)

sc-270274rGene SilencingN/A
1
(0)

Shank 3 shRNA Plasmid (r)

sc-270274-SHrGene SilencingPuromycin
1
(0)

Shank 3 shRNA (r) Lentiviral Particles

sc-270274-VrGene SilencingPuromycin
1
(0)

Shank CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Shank 2 CRISPR/Cas9 KO Plasmid (h)

sc-403143Gene Knockouth0
(0)

Shank 2 HDR Plasmid (h)

sc-403143-HDRHomology Directed Repairh0
(0)

Shank2 CRISPR/Cas9 KO Plasmid (m)

sc-431686Gene Knockoutm0
(0)

Shank 3 CRISPR/Cas9 KO Plasmid (h)

sc-437313Gene Knockouth0
(0)

Shank 3 HDR Plasmid (h)

sc-437313-HDRHomology Directed Repairh0
(0)

Shank 3 CRISPR/Cas9 KO Plasmid (m)

sc-425500Gene Knockoutm0
(0)

Shank CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Shank 1 Double Nickase Plasmid (h)

sc-403064-NICGene Knockouth0
(0)

Shank 1 Double Nickase Plasmid (h2)

sc-403064-NIC-2Gene Knockouth0
(0)

Shank CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Shank 1 CRISPR Activation Plasmid (h)

sc-403064-ACTGene Activationh0
(0)

Shank 1 CRISPR Activation Plasmid (h2)

sc-403064-ACT-2Gene Activationh0
(0)