Date published: 2026-6-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

Notch Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Notch Antibodies for research focused on understanding the Notch signaling pathway. Notch Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The Notch signaling pathway plays a critical role in cell differentiation, proliferation, and apoptosis, making it essential for proper development and tissue homeostasis. Dysregulation of Notch signaling has been implicated in various diseases, including cancer and developmental disorders, highlighting the importance of studying this pathway. Notch pathway research has revealed significant insights into cellular communication and development processes. Understanding Notch signaling mechanisms has become increasingly important in developing therapeutic strategies for various pathological conditions. Recent advances in Notch research have uncovered new regulatory mechanisms and potential therapeutic targets. Investigating Notch proteins has led to breakthroughs in understanding tissue regeneration and stem cell biology. Santa Cruz Biotechnology monoclonal antibodies for Notch research support scientists worldwide in advancing our understanding of cellular signaling and disease mechanisms.

SEE ALSO...

Notch Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Notch1 Antibody (A-8)

sc-376403mouse IgM κ2415-2453 (h)WB, IP, IF, IHC(P), ELISAm, r, h
50
(27)

Notch1 Antibody (mN1A)

sc-32745mouse IgG1 κ(m)WB, IPm, r, h
27
(13)

Notch1 Antibody (C-10)

sc-373891mouse IgG2b κ2433-2467 (h)WB, IP, IF, ELISAm, r, h
26
(7)

Notch1 Antibody (8G10)

sc-32756S. hamster IgG1299-1492 (m)WB, IP, IFm, r
8
(2)

Notch1 Antibody (E-4)

sc-373944mouse IgG2b κC-Terminal (h)WB, IP, IF, ELISAm, r, h
4
(3)

Notch1 Antibody (4i50)

sc-71719S. hamster IgG1299-1492 (m)WB, IP, IFm, r
4
(1)

Notch 2 Antibody (C-2)

sc-518049mouse IgM κ2442-2471 (m)WB, IP, IF, ELISAm, r
1
(1)

Notch 2 Antibody (F-10)

sc-518169mouse IgM κ248-272 (h)WB, IP, IF, ELISAh
2
(2)

Notch 3 Antibody (A-6)

sc-515825mouse IgM κ2290-2316 (m)WB, IP, IF, ELISAm, r, h
7
(6)

Notch 4 Antibody (A-12)

sc-393893mouse IgG2a κ1933-1964 (m)WB, IP, IF, ELISAm, r, h
10
(6)

Notch 4 Antibody (C-3)

sc-377399mouse IgG3 κ3-31 (m)WB, IP, IF, IHC(P), ELISAm, r
2
(2)

Notch siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 siRNA (h)

sc-36095hGene SilencingN/A
84
(0)

Notch1 siRNA (h2)

sc-44226hGene SilencingN/A
9
(0)

Notch1 shRNA Plasmid (h)

sc-36095-SHhGene SilencingPuromycin
84
(0)

Notch1 shRNA Plasmid (h2)

sc-44226-SHhGene SilencingPuromycin
9
(0)

Notch1 shRNA (h) Lentiviral Particles

sc-36095-VhGene SilencingPuromycin
84
(0)

Notch1 shRNA (h2) Lentiviral Particles

sc-44226-VhGene SilencingPuromycin
9
(0)

Notch1 siRNA (m)

sc-36096mGene SilencingN/A
7
(0)

Notch1 siRNA (m2)

sc-44315mGene SilencingN/A0
(0)

Notch1 shRNA Plasmid (m)

sc-36096-SHmGene SilencingPuromycin
7
(0)

Notch1 shRNA Plasmid (m2)

sc-44315-SHmGene SilencingPuromycin0
(0)

Notch1 shRNA (m) Lentiviral Particles

sc-36096-VmGene SilencingPuromycin
7
(0)

Notch1 shRNA (m2) Lentiviral Particles

sc-44315-VmGene SilencingPuromycin0
(0)

Notch1 siRNA (r)

sc-270189rGene SilencingN/A
12
(0)

Notch1 shRNA Plasmid (r)

sc-270189-SHrGene SilencingPuromycin
12
(0)

Notch1 shRNA (r) Lentiviral Particles

sc-270189-VrGene SilencingPuromycin
12
(0)

Notch 2 siRNA (h)

sc-40135hGene SilencingN/A
24
(0)

Notch 2 shRNA Plasmid (h)

sc-40135-SHhGene SilencingPuromycin
24
(0)

Notch 2 shRNA (h) Lentiviral Particles

sc-40135-VhGene SilencingPuromycin
24
(0)

Notch 2 siRNA (m)

sc-40136mGene SilencingN/A
3
(0)

Notch 2 shRNA Plasmid (m)

sc-40136-SHmGene SilencingPuromycin
3
(0)

Notch 2 shRNA (m) Lentiviral Particles

sc-40136-VmGene SilencingPuromycin
3
(0)

Notch 3 siRNA (h)

sc-37135hGene SilencingN/A
14
(0)

Notch 3 shRNA Plasmid (h)

sc-37135-SHhGene SilencingPuromycin
14
(0)

Notch 3 shRNA (h) Lentiviral Particles

sc-37135-VhGene SilencingPuromycin
14
(0)

Notch 3 siRNA (m)

sc-37136mGene SilencingN/A
6
(0)

Notch 3 shRNA Plasmid (m)

sc-37136-SHmGene SilencingPuromycin
6
(0)

Notch 3 shRNA (m) Lentiviral Particles

sc-37136-VmGene SilencingPuromycin
6
(0)

Notch 4 siRNA (h)

sc-40137hGene SilencingN/A
10
(0)

Notch 4 shRNA Plasmid (h)

sc-40137-SHhGene SilencingPuromycin
10
(0)

Notch 4 shRNA (h) Lentiviral Particles

sc-40137-VhGene SilencingPuromycin
10
(0)

Notch 4 siRNA (m)

sc-40138mGene SilencingN/A
1
(0)

Notch 4 shRNA Plasmid (m)

sc-40138-SHmGene SilencingPuromycin
1
(0)

Notch 4 shRNA (m) Lentiviral Particles

sc-40138-VmGene SilencingPuromycin
1
(0)

Notch CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Notch1 CRISPR/Cas9 KO Plasmid (h2)

sc-400167-KO-2Gene Knockouth0
(0)

Notch1 HDR Plasmid (h2)

sc-400167-HDR-2Homology Directed Repairh0
(0)

Notch1 CRISPR/Cas9 KO Plasmid (m2)

sc-421930-KO-2Gene Knockoutm0
(0)

Notch 2 CRISPR/Cas9 KO Plasmid (h2)

sc-401323-KO-2Gene Knockouth0
(0)

Notch 2 HDR Plasmid (h2)

sc-401323-HDR-2Homology Directed Repairh0
(0)

Notch 2 CRISPR/Cas9 KO Plasmid (m)

sc-421931Gene Knockoutm0
(0)

Notch 2 HDR Plasmid (m)

sc-421931-HDRHomology Directed Repairm0
(0)

Notch 3 CRISPR/Cas9 KO Plasmid (h)

sc-400424Gene Knockouth0
(0)

Notch 3 HDR Plasmid (h)

sc-400424-HDRHomology Directed Repairh0
(0)

Notch 3 CRISPR/Cas9 KO Plasmid (m)

sc-421933Gene Knockoutm0
(0)

Notch 4 CRISPR/Cas9 KO Plasmid (h)

sc-400766Gene Knockouth0
(0)

Notch 4 HDR Plasmid (h)

sc-400766-HDRHomology Directed Repairh0
(0)

Notch 4 CRISPR/Cas9 KO Plasmid (m)

sc-421934Gene Knockoutm0
(0)

Notch CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Notch1 Double Nickase Plasmid (h)

sc-400167-NICGene Knockouth0
(0)

Notch1 Double Nickase Plasmid (h2)

sc-400167-NIC-2Gene Knockouth0
(0)

Notch1 Double Nickase Plasmid (m)

sc-421930-NICGene Knockoutm0
(0)

Notch1 Double Nickase Plasmid (m2)

sc-421930-NIC-2Gene Knockoutm0
(0)

Notch 2 Double Nickase Plasmid (h)

sc-401323-NICGene Knockouth0
(0)

Notch 2 Double Nickase Plasmid (h2)

sc-401323-NIC-2Gene Knockouth0
(0)

Notch 3 Double Nickase Plasmid (h)

sc-400424-NICGene Knockouth0
(0)

Notch 3 Double Nickase Plasmid (h2)

sc-400424-NIC-2Gene Knockouth0
(0)

Notch CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Notch1 CRISPR Activation Plasmid (h)

sc-400167-ACTGene Activationh0
(0)

Notch1 Lentiviral Activation Particles (h)

sc-400167-LACGene Activationh0
(0)

Notch1 CRISPR Activation Plasmid (m)

sc-421930-ACTGene Activationm0
(0)

Notch1 Lentiviral Activation Particles (m)

sc-421930-LACGene Activationm0
(0)

Notch 2 CRISPR Activation Plasmid (h)

sc-401323-ACTGene Activationh0
(0)

Notch 2 CRISPR Activation Plasmid (h2)

sc-401323-ACT-2Gene Activationh0
(0)

Notch 2 Lentiviral Activation Particles (h)

sc-401323-LACGene Activationh0
(0)

Notch 3 CRISPR Activation Plasmid (h)

sc-400424-ACTGene Activationh0
(0)

Notch 3 CRISPR Activation Plasmid (m)

sc-421933-ACTGene Activationm0
(0)

Notch 3 Lentiviral Activation Particles (m)

sc-421933-LACGene Activationm0
(0)

Notch 4 CRISPR Activation Plasmid (h)

sc-400766-ACTGene Activationh0
(0)