Date published: 2026-4-25

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NKCC Antibodies

Santa Cruz Biotechnology features a diverse variety of NKCC Antibodies for advanced research in cellular physiology and signaling pathways. NKCC Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The Na-K-2Cl cotransporter (NKCC) plays a crucial role in maintaining cellular ion balance and regulating cell volume, which is essential for numerous physiological processes. Dysregulation of NKCC has been implicated in various pathophysiological conditions, including hypertension and neurological disorders, making it a significant target for therapeutic intervention. Understanding the function and regulation of NKCC is vital for advancing our knowledge of cellular homeostasis and developing potential treatments. NKCC research continues to reveal new insights into ion transport mechanisms and their impact on cellular function. Investigating NKCC expression patterns helps identify potential therapeutic targets in various disease states. Exploring NKCC's role in different tissue types provides valuable information about ion transport regulation. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of NKCC's role in health and disease.

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NKCC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

NKCC1 Antibody (A-6)

sc-514774mouse IgG2a κ886-1015 (h)WB, IP, IF, ELISAm, r, h
3
(3)

NKCC1 Antibody (F-4)

sc-514858mouse IgG2a κ78-99 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

NKCC2 Antibody (4H4)

sc-293222mouse IgG2a κ80-172 (h)WB, IP, ELISAh
1
(3)

NKCC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC1 CRISPR/Cas9 KO Plasmid (h)

sc-416328hGene KnockoutGFP0
(0)

NKCC1 HDR Plasmid (h)

sc-416328-HDRhHomology Directed RepairPuromycin0
(0)

NKCC1 Double Nickase Plasmid (h)

sc-416328-NIChGene KnockoutPuromycin0
(0)

NKCC1 Double Nickase Plasmid (h2)

sc-416328-NIC-2hGene KnockoutPuromycin0
(0)

NKCC1 CRISPR/Cas9 KO Plasmid (m)

sc-422971mGene KnockoutGFP0
(0)

NKCC1 HDR Plasmid (m)

sc-422971-HDRmHomology Directed RepairPuromycin0
(0)

NKCC2 CRISPR/Cas9 KO Plasmid (h2)

sc-401707-KO-2hGene KnockoutGFP0
(0)

NKCC2 HDR Plasmid (h2)

sc-401707-HDR-2hHomology Directed RepairPuromycin0
(0)

NKCC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC1 CRISPR Activation Plasmid (m)

sc-422971-ACTmGene ActivationPuro, Blast, Hygro0
(0)

NKCC1 CRISPR Activation Plasmid (m2)

sc-422971-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

NKCC1 Lentiviral Activation Particles (m)

sc-422971-LACmGene ActivationPuro, Blast, Hygro0
(0)

NKCC2 CRISPR Activation Plasmid (h)

sc-401707-ACThGene ActivationPuro, Blast, Hygro0
(0)

NKCC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NKCC siRNA (h)

sc-43972hGene SilencingN/A0
(0)

NKCC shRNA Plasmid (h)

sc-43972-SHhGene SilencingPuromycin0
(0)

NKCC shRNA (h) Lentiviral Particles

sc-43972-VhGene SilencingPuromycin0
(0)

NKCC1 siRNA (m)

sc-36072mGene SilencingN/A0
(0)

NKCC1 shRNA Plasmid (m)

sc-36072-SHmGene SilencingPuromycin0
(0)

NKCC1 shRNA (m) Lentiviral Particles

sc-36072-VmGene SilencingPuromycin0
(0)

NKCC1 siRNA (r)

sc-270468rGene SilencingN/A0
(0)

NKCC1 shRNA Plasmid (r)

sc-270468-SHrGene SilencingPuromycin0
(0)

NKCC1 shRNA (r) Lentiviral Particles

sc-270468-VrGene SilencingPuromycin0
(0)

NKCC2 siRNA (h)

sc-42517hGene SilencingN/A0
(0)

NKCC2 shRNA Plasmid (h)

sc-42517-SHhGene SilencingPuromycin0
(0)

NKCC2 shRNA (h) Lentiviral Particles

sc-42517-VhGene SilencingPuromycin0
(0)

NKCC2 siRNA (m)

sc-42518mGene SilencingN/A0
(0)

NKCC2 shRNA Plasmid (m)

sc-42518-SHmGene SilencingPuromycin0
(0)

NKCC2 shRNA (m) Lentiviral Particles

sc-42518-VmGene SilencingPuromycin0
(0)