Date published: 2026-5-13

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MBD Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of MBD Antibodies for advanced research in the field of epigenetics. MBD Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MBD proteins, or methyl-CpG binding domain proteins, play a crucial role in recognizing and binding to methylated DNA, thereby influencing gene expression and chromatin structure. The function of MBD proteins is essential in processes such as transcriptional regulation, genomic stability, and the maintenance of cellular identity. Understanding MBD proteins has significant implications for research into various diseases, including cancer and neurological disorders. Researchers worldwide rely on MBD monoclonal antibodies to advance their studies in DNA methylation patterns and chromatin modifications. The high specificity of MBD monoclonal antibodies enables precise detection and analysis of methylation-dependent protein interactions. MBD research continues to reveal new insights into epigenetic regulation mechanisms. Santa Cruz Biotechnology monoclonal antibodies for MBD proteins support researchers in making meaningful contributions to epigenetics research and disease understanding.

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MBD Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MBD1 Antibody (B-5)

sc-25261mouse IgG1 κ383-636 (m)WB, IP, IF, ELISAm, r, h
4
(4)

MBD1 Antibody (100B272.1)

sc-52901mouse IgG1FL (h)WB, IPh

new

(1)

MBD1 Antibody (A-5)

sc-55473mouse IgG1 κ383-636 (m)WB, IP, IF, ELISAm, r, h
1
(1)

MBD2 Antibody (C-11)

sc-514062mouse IgG1 κ1-70 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(5)

MBD2/3 Antibody (D-7)

sc-271562mouse IgG2b κ242-291 (h)WB, IP, IF, IHC(P), ELISAh
1
(4)

MBD2/3 Antibody (B-12)

sc-271522mouse IgG2a κ242-291 (h)WB, IP, IF, ELISAh
1
(3)

MBD2/3 Antibody (E-8)

sc-271521mouse IgG2a κ242-291 (h)WB, IP, IF, IHC(P), ELISAh
5
(3)

MBD3 Antibody (F-11)

sc-166319mouse IgG2a κ234-267 (h)WB, IP, IF, ELISAm, r, h

new

(2)

MBD4 Antibody (D-6)

sc-271530mouse IgG1 κ515-555 (m)WB, IP, IF, ELISAm, r, h

new

(3)

MBD4 Antibody (A-8)

sc-365974mouse IgG2a κ281-580 (h)WB, IP, IF, ELISAm, r, h
3
(4)

MBD4 Antibody (G-7)

sc-398249mouse IgG1 κ521-546 (m)WB, IP, IF, ELISAm, r, h

new

(1)

MBD CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBD2 CRISPR/Cas9 KO Plasmid (h)

sc-401561hGene KnockoutGFP0
(0)

MBD2 HDR Plasmid (h)

sc-401561-HDRhHomology Directed RepairPuromycin0
(0)

MBD3 CRISPR/Cas9 KO Plasmid (h)

sc-401072hGene KnockoutGFP0
(0)

MBD3 CRISPR/Cas9 KO Plasmid (m)

sc-421578mGene KnockoutGFP0
(0)

MBD4 CRISPR/Cas9 KO Plasmid (h)

sc-403156hGene KnockoutGFP0
(0)

MBD4 HDR Plasmid (h)

sc-403156-HDRhHomology Directed RepairPuromycin0
(0)

MBD4 Double Nickase Plasmid (h)

sc-403156-NIChGene KnockoutPuromycin0
(0)

MBD6 CRISPR/Cas9 KO Plasmid (h)

sc-414039hGene KnockoutGFP0
(0)

MBD6 HDR Plasmid (h)

sc-414039-HDRhHomology Directed RepairPuromycin0
(0)

MBD6 Double Nickase Plasmid (h)

sc-414039-NIChGene KnockoutPuromycin0
(0)

MBD CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBD2 CRISPR Activation Plasmid (h)

sc-401561-ACThGene ActivationPuro, Blast, Hygro0
(0)

MBD3 CRISPR Activation Plasmid (h)

sc-401072-ACThGene ActivationPuro, Blast, Hygro0
(0)

MBD4 CRISPR Activation Plasmid (h)

sc-403156-ACThGene ActivationPuro, Blast, Hygro0
(0)

MBD4 CRISPR Activation Plasmid (h2)

sc-403156-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MBD siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MBD1 siRNA (h)

sc-35863hGene SilencingN/A
1
(0)

MBD1 shRNA Plasmid (h)

sc-35863-SHhGene SilencingPuromycin
1
(0)

MBD1 shRNA (h) Lentiviral Particles

sc-35863-VhGene SilencingPuromycin
1
(0)

MBD1 siRNA (m)

sc-35864mGene SilencingN/A
1
(0)

MBD1 shRNA Plasmid (m)

sc-35864-SHmGene SilencingPuromycin
1
(0)

MBD1 shRNA (m) Lentiviral Particles

sc-35864-VmGene SilencingPuromycin
1
(0)

MBD2 siRNA (h)

sc-35865hGene SilencingN/A0
(0)

MBD2 siRNA (h2)

sc-156060hGene SilencingN/A0
(0)

MBD2 shRNA Plasmid (h)

sc-35865-SHhGene SilencingPuromycin0
(0)

MBD2 shRNA Plasmid (h2)

sc-156060-SHhGene SilencingPuromycin0
(0)

MBD2 shRNA (h) Lentiviral Particles

sc-35865-VhGene SilencingPuromycin0
(0)

MBD2 shRNA (h2) Lentiviral Particles

sc-156060-VhGene SilencingPuromycin0
(0)

MBD2 siRNA (m)

sc-35866mGene SilencingN/A
3
(0)

MBD2 shRNA Plasmid (m)

sc-35866-SHmGene SilencingPuromycin
3
(0)

MBD2 shRNA (m) Lentiviral Particles

sc-35866-VmGene SilencingPuromycin
3
(0)

MBD3 siRNA (h)

sc-35867hGene SilencingN/A
1
(0)

MBD3 shRNA Plasmid (h)

sc-35867-SHhGene SilencingPuromycin
1
(0)

MBD3 shRNA (h) Lentiviral Particles

sc-35867-VhGene SilencingPuromycin
1
(0)

MBD3 siRNA (m)

sc-35868mGene SilencingN/A0
(0)

MBD3 shRNA Plasmid (m)

sc-35868-SHmGene SilencingPuromycin0
(0)

MBD3 shRNA (m) Lentiviral Particles

sc-35868-VmGene SilencingPuromycin0
(0)

MBD4 siRNA (h)

sc-37763hGene SilencingN/A
1
(0)

MBD4 shRNA Plasmid (h)

sc-37763-SHhGene SilencingPuromycin
1
(0)

MBD4 shRNA (h) Lentiviral Particles

sc-37763-VhGene SilencingPuromycin
1
(0)

MBD4 siRNA (m)

sc-37764mGene SilencingN/A0
(0)

MBD4 shRNA Plasmid (m)

sc-37764-SHmGene SilencingPuromycin0
(0)

MBD4 shRNA (m) Lentiviral Particles

sc-37764-VmGene SilencingPuromycin0
(0)

MBD5 siRNA (h)

sc-94756hGene SilencingN/A0
(0)

MBD5 shRNA Plasmid (h)

sc-94756-SHhGene SilencingPuromycin0
(0)

MBD5 shRNA (h) Lentiviral Particles

sc-94756-VhGene SilencingPuromycin0
(0)

MBD6 siRNA (h)

sc-96201hGene SilencingN/A0
(0)

MBD6 shRNA Plasmid (h)

sc-96201-SHhGene SilencingPuromycin0
(0)

MBD6 shRNA (h) Lentiviral Particles

sc-96201-VhGene SilencingPuromycin0
(0)

MBD6 siRNA (m)

sc-149306mGene SilencingN/A0
(0)

MBD6 shRNA Plasmid (m)

sc-149306-SHmGene SilencingPuromycin0
(0)

MBD6 shRNA (m) Lentiviral Particles

sc-149306-VmGene SilencingPuromycin0
(0)

MBD3L1 siRNA (h)

sc-97409hGene SilencingN/A0
(0)

MBD3L1 shRNA Plasmid (h)

sc-97409-SHhGene SilencingPuromycin0
(0)

MBD3L1 shRNA (h) Lentiviral Particles

sc-97409-VhGene SilencingPuromycin0
(0)

MBD3L1 siRNA (m)

sc-149303mGene SilencingN/A0
(0)

MBD3L1 shRNA Plasmid (m)

sc-149303-SHmGene SilencingPuromycin0
(0)

MBD3L1 shRNA (m) Lentiviral Particles

sc-149303-VmGene SilencingPuromycin0
(0)

MBD3L2 siRNA (m)

sc-149304mGene SilencingN/A0
(0)

MBD3L2 shRNA Plasmid (m)

sc-149304-SHmGene SilencingPuromycin0
(0)

MBD3L2 shRNA (m) Lentiviral Particles

sc-149304-VmGene SilencingPuromycin0
(0)