Date published: 2025-10-11

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FLJ20433 Aktivatoren

The nomenclature FLJ20433 Activators implies a theoretical group of chemical compounds devised to enhance the activity of the protein encoded by the FLJ20433 gene. The FLJ acronym typically denotes full-length long Japan, a naming convention arising from a project aimed at discovering full-length long cDNA sequences in the Japanese population. Activators is purely speculative and does not correspond to any known chemical class. Should such a protein exist and be identified, activators would be molecules that interact with this protein to upregulate its function. These activators could potentially work by a variety of mechanisms, such as binding to the protein to stabilize its active form, increasing its expression through transcriptional regulation, or enhancing its interaction with other cellular components. The specific chemical properties of FLJ20433 Activators would depend significantly on the tertiary and quaternary structure of the FLJ20433 protein, as well as its role within the cellular machinery.

In the scenario of FLJ20433 Activators' development, the first step would be to ascertain the biological function of the FLJ20433 protein. This would likely entail a combination of genomic, proteomic, and bioinformatic techniques to map out the protein's structure, its domains of activity, and its cellular localization. Understanding the protein's role within the cell would be pivotal, and this could involve delving into its involvement in cellular processes, its interaction networks, and its regulation both at the genetic and post-translational levels. Once a comprehensive understanding of FLJ20433 is obtained, attention would turn to the chemical design of activators. These activators would be synthesized based on the structure of the protein and predicted interaction sites using computational chemistry and molecular modeling. The design process would also draw on knowledge from related proteins or homologous systems, where available. Subsequent experimental phases would involve in vitro and in vivo assays to test the compounds' efficacy in activating the FLJ20433 protein. These assays would measure not only the binding affinity and specificity of the activators but also their capacity to modulate the protein's activity in a controlled manner. Through this iterative process of hypothesis, design, synthesis, and testing, a class of FLJ20433 Activators could potentially be produced, offering insight into the biological function of the protein and serving as molecular probes for further scientific inquiry.

Siehe auch...

ProduktCAS #Katalog #MengePreisReferenzenBewertung

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$76.00
$255.00
18
(1)

Verursacht DNA-Schäden durch Hemmung der Ribonukleotid-Reduktase und induziert möglicherweise DNA-Reparaturenzyme einschließlich EXD3.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$76.00
$216.00
101
(4)

Bildet DNA-Addukte, die zu DNA-Schäden führen, wodurch DNA-Reparaturproteine wie EXD3 hochreguliert werden können.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Verursacht DNA-Strangbrüche durch Hemmung der Topoisomerase II und fördert möglicherweise die Expression von DNA-Reparaturenzymen.

Methyl methanesulfonate

66-27-3sc-250376
sc-250376A
5 g
25 g
$55.00
$130.00
2
(2)

Alkylierungsmittel, das DNA-Schäden verursacht und möglicherweise die Expression von DNA-Reparaturwegen einschließlich EXD3 auslöst.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$173.00
$418.00
43
(3)

Ein Anthrazyklin, das sich in die DNA einlagert, Schäden verursacht und möglicherweise DNA-Reparaturmechanismen auslöst.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Verknüpft die DNA, was zu einer Steigerung der DNA-Reparaturaktivität führt, die auch die Expression von EXD3 einschließen könnte.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Hemmt die Topoisomerase I, was zu DNA-Brüchen führt und möglicherweise DNA-Reparaturenzyme wie EXD3 hochreguliert.

Bleomycin

11056-06-7sc-507293
5 mg
$270.00
5
(0)

Induziert die DNA-Spaltung und erhöht möglicherweise die Expression von Genen, die an der DNA-Reparatur beteiligt sind, wie z. B. EXD3.

Benzo[a]pyrene

50-32-8sc-257130
1 g
$439.00
4
(1)

Ein polyzyklischer aromatischer Kohlenwasserstoff, der DNA-Addukte bildet und möglicherweise die Expression von DNA-Reparaturgenen induziert.

Acrylamide Solution, 40%

79-06-1sc-3721
1 L
$98.00
(1)

Kann DNA-Addukte bilden, die zu Genomschäden führen und möglicherweise die DNA-Reparaturmechanismen einschließlich der EXD3-Expression hochregulieren.