ZP3 Activators
The ZP3 Activators are a group of chemicals that enhance the functional activity of ZP3 primarily through estrogen receptor activation. These activators, which include both steroidal hormones such as estradiol and progesterone, and plant-derived phytoestrogens such as genistein and daidzein, can increase the expression of ZP3. The enhanced expression is an outcome of the regulatory role that estrogen signaling plays in the transcription of zona pellucida genes, including ZP3.
Moreover, synthetic and naturally occurring compounds that mimic estrogen, such as diethylstilbestrol and bisphenol A, and compounds with estrogenic activity, like resveratrol and zearalenone, can enhance ZP3 expression via the same mechanism. Other chemicals, such as the isoflavandiol equol and the isoflavone formononetin, also bind to and activate the estrogen receptor, subsequently enhancing ZP3 expression. Therefore, all these chemicals can enhance the functional activity of ZP3 by influencing the estrogen signaling pathway, which directly controls the expression of ZP3.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
This steroid hormone activates the estrogen receptor. This activation can enhance ZP3 expression, as estrogen signaling has been implicated in the regulation of zona pellucida genes, including ZP3. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $52.00 $298.00 | 3 | |
This steroid hormone, through its receptor, can enhance ZP3 expression. Progesterone receptor signaling plays a role in the regulation of zona pellucida genes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
This isoflavone, found in soy products, acts as a phytoestrogen, activating estrogen receptors. This activation can enhance ZP3 expression, as estrogen signaling is known to regulate zona pellucida genes. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $28.00 $79.00 $165.00 | 32 | |
Another isoflavone, daidzein also acts as a phytoestrogen, activating estrogen receptors. This mechanism can enhance ZP3 expression due to the role of estrogen signaling in regulating zona pellucida genes. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
This organic compound can mimic estrogen, activating the estrogen receptor. Activation of this pathway can enhance ZP3 expression, given the role of estrogen signaling in regulating zona pellucida genes. | ||||||
Diethylstilbestrol | 56-53-1 | sc-204720 sc-204720A sc-204720B sc-204720C sc-204720D | 1 g 5 g 25 g 50 g 100 g | $71.00 $287.00 $547.00 $1098.00 $2185.00 | 3 | |
This synthetic nonsteroidal estrogen can activate the estrogen receptor, potentially enhancing ZP3 expression due to the regulatory role of estrogen signaling in zona pellucida genes. | ||||||
Coumestrol | 479-13-0 | sc-205638 sc-205638A | 10 mg 25 mg | $207.00 $321.00 | 2 | |
This organic compound acts as a phytoestrogen, activating the estrogen receptor. This activation can enhance ZP3 expression due to the role of estrogen signaling in regulating zona pellucida genes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
This polyphenolic compound has estrogenic activity, activating the estrogen receptor. This activation can enhance ZP3 expression, as estrogen signaling is known to regulate zona pellucida genes. | ||||||
Zearalenone | 17924-92-4 | sc-204943 sc-204943A | 10 mg 50 mg | $120.00 $369.00 | 6 | |
This mycotoxin has estrogenic activity, activating the estrogen receptor. This activation can enhance ZP3 expression due to the role of estrogen signaling in regulating zona pellucida genes. | ||||||
rac Enterolactone | 78473-71-9 | sc-498620 | 500 µg | $305.00 | ||
This lignan metabolite has estrogenic activity, activating the estrogen receptor. This activation can enhance ZP3 expression, given the role of estrogen signaling in regulating zona pellucida genes. | ||||||