Coumestrol CAS: 479-13-0
MF: C15H8O5
MW: 268.22
A plant estrogen & highly potent inhibitor of 17-β-hydroxysteroid oxidoreductase.

Coumestrol (CAS 479-13-0)

Coumestrol | CAS 479-13-0 is rated 5.0 out of 5 by 1.
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Synonym: Cumoesterol; 3,9-Dihydroxycoumestan; 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one
Application: A plant estrogen & highly potent inhibitor of 17-β-hydroxysteroid oxidoreductase
CAS Number: 479-13-0
Molecular Weight: 268.22
Molecular Formula: C15H8O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Coumestrol is a plant estrogen and highly potent inhibitor of 17 β-HSD (17-β-hydroxysteroid oxidoreductase). Coumestrol is an inhibitor of ER α and ER β.


References

1. Poutanen, M., et al. 1995. Proc. Soc. Exp. Biol. Med. 208: 51-59. PMID: 7892295

Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
385°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5281707
SMILES :
C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O

Download SDS (MSDS)

Certificate of Analysis

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Coumestrol  Product Citations

See how others have used Coumestrol. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27709316  You, JS. et al. 2017. Inflammation. 40: 79-91.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Makela et al Makela et al. (PubMed ID 7892295) found that the plant estrogen, coumestrol, lowered the conversion of [3H]estrone to [3H] 17 beta-estradiol via 17 beta-HSOR Type 1 inhibition. -SCBT Publication Review
Date published: 2015-06-08
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