ZNF721 Activators
Common ZNF721 Activators include, but are not limited to Trichostatin A CAS 58880-19-6, 5-Azacytidine CAS 320-67-2, Chaetocin CAS 28097-03-2, α-Amanitin CAS 23109-05-9 and Retinoic Acid, all trans CAS 302-79-4.
ZNF721, officially termed Zinc Finger Protein 721 or KIAA1982, is a protein-coding gene located on chromosome 4 at the specific position 4p16.3. This gene is tied to the condition known as Patella Chondromalacia, characterized by the softening or degeneration of the cartilage found beneath the kneecap. Functionally, ZNF721 plays a role in pathways related to gene expression, especially in the domain of transcription. As part of the Zinc fingers C2H2-type gene family, ZNF721 is implicated in DNA-binding and transcriptional regulation activities. Such classification aligns with the prediction that the protein encoded by ZNF721 predominantly operates in the nucleus, given its role in transcriptional regulation.
ZNF721 activators, as the name suggests, are chemical compounds or agents that promote or enhance the activity of the ZNF721 gene or its encoded protein. These activators can enhance the gene's transcription, upregulate its expression, or potentiate the activity of the protein product. Given the gene's involvement in DNA-binding and transcriptional regulation, it's conceivable that its activators might influence various cellular processes, including those associated with gene expression and regulatory pathways. However, as of now, specifics regarding ZNF721 activators, including their structures, mechanisms of action, and potential applications, remain largely unknown. While the presented data provides a foundational understanding of ZNF721 and its activators, there's a noticeable gap in knowledge regarding its specific molecular functions, interactions, and broader physiological implications. To gain a comprehensive understanding of ZNF721 and its activators, more thorough exploration into academic literature, genomic databases, and scientific studies would be essential. Such investigations could illuminate the multifaceted roles of ZNF721 in cellular processes and its significance in human health, as well as the potential impact of its activators.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an HDAC inhibitor, it may promote a more relaxed chromatin structure, potentially enhancing the accessibility of transcription factors and cofactors to the ZNF721 gene promoter region. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By inhibiting DNA methylation, it might promote a more transcriptionally permissive state at the ZNF721 locus, potentially leading to increased gene expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET bromodomain inhibition might affect the binding of bromodomain-containing proteins to acetylated histones at the ZNF721 gene locus, possibly influencing its expression. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
By inhibiting histone methyltransferase activity, it may alter the methylation status of histones associated with the ZNF721 gene, potentially influencing its expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Although it's a potent inhibitor of RNA polymerase II and would generally suppress transcription, in a more complex scenario it could potentially influence compensatory mechanisms that might upregulate ZNF721 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
It might affect gene expression through retinoic acid receptors and their interaction with regulatory regions of the ZNF721 gene. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
As a glucocorticoid, it might influence ZNF721 expression through glucocorticoid receptor-mediated transcriptional regulation. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
By inhibiting protein kinase activity, it might influence signaling pathways that modulate ZNF721 expression. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Phosphatase inhibition could affect phosphorylation states of transcriptional regulators or signaling molecules, potentially influencing ZNF721 expression. | ||||||
BAY 11-7085 | 196309-76-9 | sc-202490 sc-202490A | 10 mg 50 mg | $122.00 $516.00 | 55 | |
By inhibiting the NF-κB pathway, it might modulate signaling pathways that could influence ZNF721 expression. | ||||||