ZNF585A Inhibitors
Chemicals classified as ZNF585A Inhibitors aim to indirectly target the protein by affecting the cellular pathways or processes it may participate in. For example, compounds like RGFP966 and 5-Aza-2'-deoxycytidine focus on altering gene expression at the epigenetic level. RGFP966, an HDAC inhibitor, would affect the deacetylation state of histones, possibly altering the transcriptional activity of ZNF585A. On the other hand, 5-Aza-2'-deoxycytidine inhibits DNA methyltransferase, which would impact ZNF585A's role if it is involved in DNA methylation for gene regulation.
Likewise, compounds like I-BET151 and JQ1 target the bromodomain-containing proteins that interact with acetylated histones. If ZNF585A functions through bromodomains, then inhibiting them can diminish its activity. Other inhibitors like Triptolide, Dasatinib, and Nutlin-3a function by targeting key proteins in major cellular pathways like NF-kB, Src kinases, and the p53-MDM2 axis, respectively. If ZNF585A is involved in any of these pathways, its functional role can be affected by these inhibitors. These chemicals serve as tools for cellular pathway manipulation where ZNF585A operates, providing the avenue to modulate its function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
Histone deacetylase inhibitor; ZNF585A is a zinc-finger protein potentially involved in gene regulation. Inhibiting histone deacetylation can affect its ability to regulate target genes. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
DNA methyltransferase inhibitor; if ZNF585A is implicated in DNA methylation, inhibition of DNA methyltransferase can modulate its function. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
NF-kB inhibitor; if ZNF585A operates in the NF-kB pathway, triptolide can block its functional implications. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET bromodomain inhibitor; if ZNF585A interacts with chromatin via bromodomains, its function will be hindered by I-BET151. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET bromodomain inhibitor; if ZNF585A interacts with bromodomains in chromatin, JQ1 can inhibit this interaction, affecting its activity. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Src kinase inhibitor; if ZNF585A operates downstream of Src kinase, its functionality can be compromised. | ||||||
(–)-Nutlin-3 | 675576-98-4 | sc-222086 sc-222086A | 1 mg 5 mg | $122.00 $219.00 | 2 | |
MDM2 inhibitor; if ZNF585A interacts with p53, inhibition of MDM2 can enhance p53 activity, which in turn may inhibit ZNF585A. | ||||||
Obatoclax Mesylate | 803712-79-0 | sc-364221 sc-364221A | 5 mg 10 mg | $96.00 $141.00 | ||
Bcl-2 family inhibitor; if ZNF585A is implicated in apoptosis regulation, its function can be altered. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
GSK-3 inhibitor; if ZNF585A has a role in the Wnt signaling pathway, inhibition of GSK-3 can affect its function. | ||||||
Calpeptin | 117591-20-5 | sc-202516 sc-202516A | 10 mg 50 mg | $121.00 $456.00 | 28 | |
Calpain inhibitor; if ZNF585A is involved in calcium-dependent processes, calpeptin can modulate its function. | ||||||