ZNF517 Activators
The chemical class known as ZNF517 activators encompasses a diverse group of compounds that can interface with cellular mechanisms to modulate the activity of the zinc finger protein 517. These activators interact with various cellular pathways and processes, which can result in the activation of ZNF517, a transcription factor that binds to DNA and regulates gene expression. The primary mode by which these chemicals can activate ZNF517 is through the alteration of intracellular environments that affect the transcription machinery, either by changing the chromatin structure to make DNA more accessible to transcription factors or by influencing the signaling pathways that lead to the transcriptional activation of genes associated with ZNF517.
These activators can achieve this by acting as inhibitors or enhancers of enzymes such as DNA methyltransferases and histone deacetylases, which can modify the epigenetic landscape. Furthermore, some activators can increase intracellular messenger levels, such as cAMP, which can then activate kinase pathways, potentially leading to the phosphorylation of transcriptional regulators and affecting their activity. Other compounds can interact with cellular receptors and initiate signaling cascades that culminate in the nuclear translocation of transcription factors or the modification of transcription factor activity. The breadth of this chemical class is significant, as it includes compounds with varying structures and properties, all linked by their ability to influence the pathways that can activate ZNF517, thereby playing a pivotal role in the regulation of gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A regulator of gene expression that can influence cell differentiation and may enhance the expression of a range of transcription factors, which could possibly activate ZNF517. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
An activator of protein kinase C that can initiate various signaling cascades, potentially leading to the activation of transcription factors that could possibly activate ZNF517. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An adenylate cyclase activator that increases cAMP levels, which may subsequently activate protein kinase A (PKA) and potentially induce the activity of transcription factors that could possibly activate ZNF517. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
A cAMP analog that can activate PKA, leading to phosphorylation of target proteins and possibly influencing transcription factor activity that could possibly activate ZNF517. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol found in green tea that can modulate multiple signaling pathways and may influence the activity of various transcription factors that could possibly activate ZNF517. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
An activator of SIRT1, a deacetylase that can modulate transcription factors by altering their acetylation status, potentially affecting ZNF517. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound that can modulate various signaling pathways, potentially altering the transcriptional regulation activities of proteins that could possibly activate ZNF517. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound known to affect gene expression by influencing transcription factor NF-κB, which may also have an impact on other transcription factors that could possibly activate ZNF517. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor that can cause changes in chromatin structure, potentially affecting the binding of transcription factors to DNA that could possibly activate ZNF517. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
A GSK-3 inhibitor that can modulate Wnt signaling, potentially influencing the activity of transcription factors downstream of this pathway that could possibly activate ZNF517. | ||||||