ZNF509 Activators
ZNF509 Activators are a unique class of compounds that utilize diverse mechanisms to enhance the functional activity of the ZNF509 transcription factor. For instance, Forskolin and IBMX work synergistically to upregulate the cAMP-PKA pathway, which can facilitate ZNF509's binding to DNA. Rapamycin and LY294002, on the other hand, work by modulating cellular homeostasis and Akt signaling respectively, thereby indirectly enhancing the functioning of ZNF509. Trichostatin A and 5-Azacytidine are epigenetic modifiers that can increase ZNF509's access to its target genes by altering the chromatin structure and DNA methylation status.
Resveratrol, a SIRT1 activator, can indirectly enhance ZNF509 function by modulating the acetylation status of key proteins. PD98059 and SB203580 inhibit ERK and p38 MAPK signaling respectively, which can enhance ZNF509 function by removing negative regulation from certain transcription factors. MG132 prevents protein degradation, which could enhance ZNF509 function if it or its co-regulators are targets of proteasomal degradation. Lastly, Y-27632 and Calyculin A can influence cellular processes such as cytoskeletal dynamics and protein phosphorylation respectively, which could indirectly enhance ZNF509 function.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Adenylyl cyclase activator that leads to increased cAMP production. ZNF509 is a transcription factor and its binding to DNA can be enhanced by cAMP-dependent protein kinase (PKA) signaling. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Phosphodiesterase inhibitor that prevents the breakdown of cAMP, thereby enhancing PKA signaling and potentially the function of ZNF509. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor that can lead to increased autophagy. This may indirectly enhance ZNF509 function by maintaining cellular homeostasis, thus providing a conducive environment for ZNF509. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that can decrease Akt signaling. As Akt can negatively regulate certain transcription factors, its inhibition could potentially enhance ZNF509 function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor that can lead to a more open chromatin structure, potentially promoting ZNF509 binding to its target genes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that can lead to a less methylated DNA state, potentially promoting ZNF509 binding to its target genes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
SIRT1 activator that can promote deacetylation of certain proteins. This might indirectly enhance ZNF509 function if ZNF509 or its co-factors are targets of SIRT1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that can decrease ERK signaling. As ERK can negatively regulate certain transcription factors, its inhibition could potentially enhance ZNF509 function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor that can affect various cellular processes. This could potentially enhance ZNF509 function, given that ZNF509 is a transcription factor and its function may be influenced by the cellular context. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can prevent the degradation of proteins. This could potentially enhance the function of ZNF509 if it or its co-regulators are targets of proteasomal degradation. | ||||||