ZNF397 Activators
The chemical class known as ZNF397 Activators refers to a diverse group of compounds that are capable of modulating gene expression, either through direct effects on DNA accessibility, such as changes in chromatin structure, or through indirect effects on cellular signaling pathways that govern transcription factor activity. The compounds listed have various mechanisms of action, from altering the epigenetic landscape to affecting second messenger systems within the cell. For instance, 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors like Trichostatin A, Sodium butyrate, and SAHA can induce a more open chromatin conformation, thereby increasing the binding of ZNF397 to its cognate DNA sequences and enhancing its transcriptional activity.
Compounds such as Mithramycin A may also alter the binding dynamics of transcription factors, while signaling molecules like Retinoic acid, Forskolin, and Dibutyryl cAMP can modify the intracellular environment, thereby impacting ZNF397 indirectly. EGCG, Genistein, Sulforaphane, and Curcumin are all known to affect gene expression patterns and could play a role in the regulation of ZNF397.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, modifies chromatin structure to a more open conformation, potentially facilitating ZNF397 access to DNA. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Also a histone deacetylase inhibitor, induces chromatin remodeling which can augment ZNF397-mediated transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, may enhance ZNF397 activity by increasing transcriptional accessibility to chromatin. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
A DNA-binding antitumor antibiotic that can displace certain transcription factors, possibly increasing the availability of binding sites for ZNF397. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A, affects gene expression and could modulate the activity of ZNF397 by influencing cellular differentiation pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increases cAMP levels, and may indirectly enhance ZNF397 function by influencing cellular signaling pathways. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A cAMP analog, can activate PKA and thereby influence transcription factor activity, potentially impacting ZNF397 function. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A polyphenol from green tea, has been shown to affect gene expression and could modulate ZNF397 activity indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor, has roles in gene expression and might influence ZNF397 activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound in cruciferous vegetables, can influence gene expression and might alter ZNF397 activity. | ||||||