The conceptual category of ZFP936 Inhibitors encompasses a range of compounds that, through their action on various signaling molecules and pathways, have the potential to indirectly modulate the activity or expression of ZFP936. Given ZFP936's presumed role as a zinc finger protein involved in transcriptional regulation, the selected inhibitors target mechanisms such as DNA methylation, histone acetylation, and chromatin remodeling. These processes are crucial for the regulation of gene expression and are pathways through which ZFP936 is likely to exert its biological effects.
This approach to identifying potential inhibitors underscores the complexity of transcriptional regulation and the interconnected nature of cellular signaling networks. By targeting key regulatory processes that influence gene expression, such as chromatin accessibility and the activity of transcription factors, these inhibitors offer insights into the biological functions of ZFP936 and its role in cellular processes. Through such exploration, the selected compounds not only facilitate a deeper understanding of ZFP936's involvement in gene expression but also underscore the broader principles of cellular regulation and signal transduction. This methodology exemplifies the potential of targeted chemical intervention to modulate the function of specific proteins indirectly, providing a foundation for further research into the mechanisms of transcriptional regulation and the role of zinc finger proteins like ZFP936 in these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
DNMT inhibitor, potentially altering DNA methylation affecting ZFP936-regulated gene expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
HDAC inhibitor, could modify chromatin structure, potentially influencing ZFP936's role in transcription. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
Selective HDAC inhibitor, potentially affects chromatin accessibility and ZFP936 activity. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
Broad-spectrum HDAC inhibitor, might influence ZFP936's role in transcriptional regulation. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
DNA methyltransferase inhibitor, could affect methylation patterns of genes regulated by ZFP936. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor, potentially affecting chromatin state and gene expression regulated by ZFP936. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET bromodomain inhibitor, could disrupt protein-protein interactions affecting ZFP936 function. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET bromodomain inhibitor, might influence ZFP936-mediated gene regulation. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $90.00 $238.00 $300.00 | ||
EZH2 methyltransferase inhibitor, potentially affecting histone methylation and ZFP936 regulatory functions. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $260.00 | ||
ERK1/2 inhibitor, potentially impacts signaling pathways that ZFP936 may be involved in. | ||||||