XRRA1 Activators
X-Ray Radiation Resistance Associated 1 (XRRA1) is a protein encoded by the XRRA1 gene in humans. It is known for its association with cellular responses to ionizing radiation, contributing to cellular resistance against the damaging effects of X-ray radiation.The XRRA1 protein is thought to play a role in DNA repair pathways, specifically in the repair of DNA double-strand breaks (DSBs), which are highly detrimental DNA lesions caused by factors such as ionizing radiation. Efficient and accurate repair of DSBs is crucial for maintaining genomic stability, and defects in this process can lead to genetic mutations and chromosomal aberrations.
XRRA1 is also suggested to be involved in cell cycle control. Some studies indicate that it may play a role in the G1/S checkpoint, a critical phase during which cells either commit to DNA replication or pause for repair, thereby preventing the replication of damaged DNA. Abnormalities in XRRA1 expression or function contribute to radiation sensitivity and susceptibility to cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, known for its antioxidant and anti-inflammatory properties, might influence XRRA1 indirectly by modulating cellular responses to oxidative stress and DNA damage. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, with its antioxidant effects, could indirectly affect XRRA1 by influencing pathways involved in cellular response to oxidative stress and DNA repair. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound found in cruciferous vegetables, may indirectly affect XRRA1 activity through its role in antioxidant defense and DNA repair mechanisms. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
NAC, known for its role in replenishing glutathione, might indirectly affect XRRA1 by influencing oxidative stress response and DNA repair processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, could indirectly affect XRRA1 through its antioxidant properties and effects on DNA repair pathways. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B sc-214454C | 10 g 25 g 100 g 1 kg | $43.00 $62.00 $141.00 $430.00 | ||
Vitamin E, an antioxidant, may indirectly influence XRRA1 by protecting cells from oxidative damage and potentially influencing DNA repair mechanisms. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Lycopene, a carotenoid with antioxidant properties, might indirectly influence XRRA1 by modulating cellular antioxidant defenses. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, could indirectly affect XRRA1 through its antioxidant effects and potential role in modulating DNA repair pathways. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $65.00 $73.00 $218.00 $697.00 $1196.00 $3574.00 | 16 | |
Melatonin, known for its antioxidant and DNA protective effects, might indirectly affect XRRA1 activity. | ||||||