WDR20 Activators
WDR20 activators are compounds that indirectly affect the functionality of WDR20 by modulating cellular signaling pathways and protein interactions. Compounds such as forskolin and IBMX increase intracellular cAMP, which is a key regulator of numerous signaling cascades. Elevated cAMP levels can lead to changes in the activity of protein kinases and phosphatases that indirectly alter the functional state of WDR20. Additionally, chemicals like rolipram and epigallocatechin gallate (EGCG) can further refine the signaling landscape by their actions on specific enzymes and receptors, potentially creating a cellular context that necessitates the action of WDR20.
Moreover, agents such as lithium chloride, which impacts the Wnt signaling pathway and GSK-3 activity, can create a cascade of protein modifications, thereby indirectly influencing the functional state of WDR20. Epigenetic modifiers (5-Azacytidine, sodium butyrate) can lead to alterations in protein levels and modifications that might modulate WDR20 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Directly activates adenylyl cyclase, which increases levels of cAMP, a secondary messenger that can modulate various signaling pathways, potentially impacting WDR20 function. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, leading to increased cAMP levels, possibly affecting pathways associated with WDR20. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Specific inhibitor of phosphodiesterase 4, increases intracellular cAMP levels, which may affect signaling cascades involving WDR20. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Modulates several signal transduction pathways, potentially altering the protein interaction landscape that WDR20 is part of. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences the Wnt signaling pathway and glycogen synthase kinase 3 (GSK-3) activity, possibly impacting WDR20 through pathway interactions. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor, can cause epigenetic changes that may influence WDR20 expression and function. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Sirtuin inhibitor, affects NAD+ metabolism and may influence signaling pathways and protein interactions involving WDR20. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Influences multiple signaling pathways, including sirtuin activity, which may affect proteins interacting with WDR20. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Histone deacetylase inhibitor, alters gene expression and may influence pathways where WDR20 is involved. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Modulates gene expression through retinoic acid receptors, potentially influencing signaling pathways associated with WDR20. | ||||||