VMP1 Activators
VMP1 Activators, also known as Vacuole Membrane Protein 1 activators, belong to a distinctive chemical class of compounds that play a pivotal role in cellular homeostasis and autophagy regulation. These compounds are specifically designed to target and modulate the activity of the VMP1 protein, a critical component of the autophagic machinery. VMP1 is integral to the formation and maturation of autophagosomes, which are double-membraned vesicles responsible for sequestering and degrading cellular components, including damaged organelles and misfolded proteins. The activation of VMP1 is central to the initiation of autophagy, a highly regulated cellular process essential for maintaining cellular health and responding to various stressors.
VMP1 Activators are characterized by their ability to interact with VMP1 and stimulate its activity, thereby enhancing the autophagic process. By doing so, they promote the clearance of cellular debris and dysfunctional organelles, contributing to cellular quality control. This class of compounds is of great interest to researchers in the fields of cell biology and molecular medicine due to its potential to modulate autophagy, a process implicated in various diseases, including neurodegenerative disorders and certain cancers. The precise mechanisms by which VMP1 Activators interact with VMP1 and regulate autophagy are still under active investigation, but their development holds promise for shedding light on the fundamental processes governing cellular maintenance and repair.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
A classic autophagy inducer that activates the mTOR pathway, leading to increased VMP1 expression. | ||||||
D-(+)-Trehalose Anhydrous | 99-20-7 | sc-294151 sc-294151A sc-294151B | 1 g 25 g 100 g | $30.00 $167.00 $260.00 | 2 | |
This disaccharide has been shown to induce autophagy and upregulate VMP1 levels, promoting autophagosome formation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A natural polyphenol found in red grapes and other plants, resveratrol activates autophagy and increases VMP1 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Derived from turmeric, curcumin stimulates autophagy and enhances VMP1 expression. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
metformin also induces autophagy and upregulates VMP1 expression. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Tamoxifen induces autophagy and can upregulate VMP1 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Used as a mood stabilizer, lithium can activate autophagy and increase VMP1 levels. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
An endoplasmic reticulum stress inducer, tunicamycin triggers autophagy and VMP1 expression as a protective response. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
This synthetic glucocorticoid can induce autophagy and elevate VMP1 expression in certain cell types. | ||||||