Vgl-4 Activators
Vgl-4, also known as Vestigial-like protein 4, is a protein encoded by the VGLL4 gene in humans. It is part of the Vestigial-like protein family, which is known to be involved in transcriptional coactivation. Members of this family, including Vgl-4, are known to interact with transcription factors to modulate gene expression, playing essential roles in various cellular processes such as development, differentiation, and growth.
Vgl-4 has been particularly associated with the regulation of the Hippo signaling pathway, a crucial pathway involved in organ size control, cell proliferation, and apoptosis. Through its interaction with YAP, a major effector in the Hippo pathway, Vgl-4 can influence the transcriptional activity of various genes involved in these cellular processes. Additionally, Vgl-4 has been implicated in the suppression of cancer cell growth and invasion in various types of cancers, suggesting a potential tumor-suppressive role.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid may enhance the expression of Vgl-4 by modulating transcriptional activity and promoting cellular differentiation processes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a glucocorticoid, might influence Vgl-4 expression by interacting with glucocorticoid receptors and influencing gene transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin may elevate Vgl-4 levels by activating adenylate cyclase, increasing cAMP, and subsequently modulating gene expression. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
T3 may upregulate Vgl-4 expression by binding to thyroid hormone receptors and modulating transcription. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol may increase Vgl-4 expression through β-adrenergic receptor activation and downstream signaling pathways. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
Hydrocortisone may influence Vgl-4 transcription by interacting with glucocorticoid receptors. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein may modulate Vgl-4 expression by inhibiting tyrosine kinases and influencing transcriptional activity. | ||||||
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
This cAMP analog may mimic the action of endogenous cAMP, potentially modulating Vgl-4 expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA might induce Vgl-4 expression by activating protein kinase C (PKC) and influencing gene transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate may promote Vgl-4 expression by inhibiting histone deacetylases and facilitating transcription. | ||||||