VEST1 inhibitors are a distinctive class of chemical compounds designed to target and inhibit the activity of the VEST1 protein. VEST1, also known as Vesicular Stimulation Transporter 1, is involved in intracellular processes related to vesicular trafficking and cellular signaling. It is characterized by its role in the movement and sorting of vesicles within cells, which is crucial for maintaining various cellular functions, including the transport of proteins and other molecules between organelles. The function of VEST1 is integral to the proper operation of cellular machinery and the regulation of intracellular compartments.
The action of VEST1 inhibitors is based on their ability to bind to specific sites on the VEST1 protein, thereby preventing it from performing its normal functions. This binding disrupts the protein's involvement in vesicular transport and sorting processes. By inhibiting VEST1, these compounds can alter the normal trafficking of vesicles and the distribution of their contents, which can affect a wide range of cellular activities. Researchers utilize VEST1 inhibitors to study the precise role of this protein in cellular logistics and signaling, providing insights into how disturbances in vesicular transport can influence overall cellular function and organization. These inhibitors are instrumental in understanding the dynamics of vesicle-mediated processes and how VEST1 contributes to cellular homeostasis and intracellular communication.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Interacts with DNA and inhibits RNA polymerase, potentially reducing C8orf34 mRNA synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Inhibits RNA polymerase II, potentially decreasing C8orf34 transcription. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Alters transcriptional activity, which may lead to decreased C8orf34 gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Incorporates into DNA and disrupts methylation, possibly reducing C8orf34 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylases, potentially affecting C8orf34 chromatin structure and expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Binds to bacterial RNA polymerase, but might also affect eukaryotic RNA polymerase, potentially influencing C8orf34 expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II transcription elongation, which could suppress C8orf34 expression. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Shortens RNA poly(A) tails, which could lead to reduced stability of C8orf34 mRNA. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Inhibits DNA topoisomerase I, potentially reducing C8orf34 expression by affecting DNA replication and transcription. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to GC-rich DNA sequences and could inhibit the transcription of C8orf34 if its promoter is GC-rich. | ||||||