V3R 4 Activators comprise a diverse array of chemical compounds that orchestrate a symphony of biochemical pathways to enhance the functionality of V3R 4. Resveratrol and Curcumin lead this ensemble by modulating sirtuin and NF-κB pathways, respectively, setting the stage for V3R 4 activation. Resveratrol's interaction with SIRT1 triggers downstream effects that prime the cellular environment for V3R 4 activity, while Curcumin's anti-inflammatory properties create a milieu that favors V3R 4's functional enhancement. Sulforaphane and Epigallocatechin Gallate (EGCG) contribute to this milieu by activating Nrf2 and inhibiting NF-κB, respectively, both actions fostering an antioxidative and anti-inflammatory environment conducive to V3R 4 activation. Quercetin and Silymarin add complexity to this mix by modulating the PI3K/AKT and oxidative stress pathways. This modulation subtly reshapes the cellular landscape, indirectly supporting V3R 4's role in cell survival and metabolism.
The second phase of this biochemical orchestration involves Berberine, Caffeic Acid Phenethyl Ester (CAPE), Genistein, Indole-3-Carbinol, Piperine, and Lycopene, each bringing a unique mechanism to enhance V3R 4 activity. Berberine's activation of the AMPK pathway influences metabolic processes that indirectly augment V3R 4 functionality, while CAPE's modulation of NF-κB further diminishes pro-inflammatory signaling, enhancing V3R 4's role. Genistein's tyrosine kinase inhibition indirectly modulates pathways that intersect with V3R 4's functional spectrum. Similarly, Indole-3-Carbinol's impact on estrogen receptor signaling indirectly affects V3R 4, highlighting the complex interplay of hormonal and enzymatic pathways in V3R 4 activation. Piperine's influence on metabolic enzymes and transporters, along with Lycopene's role in modulating antioxidant responses, further underscores the intricate web of interactions that culminate in the enhanced functionality of V3R 4. Together, these activators illuminate the multifaceted nature of biochemical pathways influencing V3R 4, revealing a nuanced landscape of indirect yet potent mechanisms enhancing its activity.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol enhances V3R 4 activity by modulating sirtuin pathways, particularly SIRT1. Activation of SIRT1 leads to downstream signaling events that result in the functional enhancement of V3R 4. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin indirectly enhances V3R 4 activity through its anti-inflammatory effects, which modulate NF-κB pathways. This modulation can lead to an environment that promotes V3R 4 activation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane activates Nrf2, a transcription factor that indirectly upregulates V3R 4 activity by initiating antioxidant response pathways, thereby creating a cellular environment conducive to V3R 4 activation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, primarily known for its antioxidant properties, indirectly enhances V3R 4 activity by inhibiting NF-κB, leading to reduced inflammatory signaling and thus promoting V3R 4 activation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin increases V3R 4 activity by modulating PI3K/AKT pathways, which are involved in cell survival and metabolism, indirectly supporting V3R 4 functionality. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $319.00 | ||
Silymarin enhances V3R 4 activity by modulating liver enzymes and oxidative stress pathways, indirectly creating a favorable environment for V3R 4 activation. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine promotes V3R 4 activity through AMPK pathway activation, which in turn influences metabolic pathways indirectly associated with V3R 4 functionality. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein influences V3R 4 activity by inhibiting tyrosine kinases, thus impacting signaling pathways that indirectly modulate V3R 4 activity. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Indole-3-Carbinol enhances V3R 4 activity by modulating estrogen receptor signaling, which indirectly affects pathways involved in V3R 4 functionality. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $36.00 $143.00 | 3 | |
Piperine indirectly enhances V3R 4 activity by influencing metabolic enzymes and transporters, thereby modifying the cellular environment in a way that supports V3R 4 activity. |