UTP6 Inhibitors
UTP6 inhibitors LY294002 and Wortmannin are both inhibitors of the PI3K family, which play a pivotal role in transducing signals from growth factors and other extracellular stimuli to intracellular responses, including those related to protein synthesis and turnover. PD98059, U0126, and SB203580 belong to the class of MAPK pathway inhibitors, which are crucial in regulating cellular responses to a variety of stimuli, impacting protein expression and activity.
Rapamycin is an inhibitor of the mTOR pathway, which is central to cell growth and metabolism. Inhibition of mTOR can influence numerous proteins that facilitate cell cycle progression and growth. PP2 and Genistein impact protein function by inhibiting tyrosine kinases, which are important for the activation of many types of cellular proteins. The JNK pathway, targeted by SP600125, is involved in stress response and apoptosis, thereby influencing protein function related to these processes. NF449 and Brefeldin A disrupt G-protein signaling and protein trafficking, respectively, pointing to a broad impact on protein function and signaling. Finally, Y-27632 inhibits ROCK, which is involved in regulating cell shape, motility, and contraction, all of which can impact the function of proteins related to these cellular events.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A specific inhibitor of phosphoinositide 3-kinases (PI3K), which can indirectly affect proteins regulated by PI3K signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of mitogen-activated protein kinase kinase (MEK), which can alter the function of proteins downstream of the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A selective inhibitor of p38 MAPK, which can modulate proteins involved in the p38 MAPK signaling cascade. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A potent inhibitor of PI3K, which can affect proteins that are part of the PI3K/Akt pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, which can influence proteins associated with the mTOR signaling pathway. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
An Src family kinase inhibitor, which can alter the activity of proteins that are regulated by Src kinase signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which can affect protein function within the JNK signaling pathway. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
A selective G-protein antagonist, which can inhibit proteins that interact with G-protein coupled receptors. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
An inhibitor of ADP-ribosylation factor (ARF), which can disrupt protein trafficking and signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
An inhibitor of the Rho-associated protein kinase (ROCK), which can affect proteins involved in the Rho/ROCK pathway. | ||||||