UTP11L Activators represent a specific category of chemical compounds designed to modulate the activity of the UTP11L gene or protein. UTP11L, also known as U3 Small Nucleolar RNA-Associated Protein 11-Like, is a gene that encodes a protein involved in the biogenesis and processing of ribosomal RNA (rRNA). This essential cellular process is crucial for the production of functional ribosomes, which are fundamental components of the cellular machinery responsible for protein synthesis. The precise biological functions and regulatory mechanisms of UTP11L are subjects of ongoing research within the field of molecular biology and cell biology. Activators in the UTP11L Activators class typically consist of small molecules or chemical agents strategically designed to interact with the UTP11L gene or protein, with the aim of enhancing its expression or influencing its functional capabilities. These activators serve as valuable tools for researchers to manipulate UTP11L-related processes and explore its potential functions in the context of ribosomal RNA biogenesis.
The mechanism of action for UTP11L Activators may encompass various aspects of gene regulation or protein function. These compounds could influence the binding of transcription factors to the promoter region of the UTP11L gene, potentially increasing its transcriptional activity and leading to elevated UTP11L gene expression levels in specific cell types or during specific cellular conditions. Additionally, UTP11L Activators might affect the post-translational modifications or interactions of the UTP11L protein, modulating its role in ribosomal RNA processing or other cellular processes related to ribosome biogenesis. Researchers and scientists employ UTP11L Activators in molecular and cell biology studies to investigate the roles of UTP11L in ribosomal RNA biogenesis and the formation of functional ribosomes. By selectively modulating the gene's activity or protein function, researchers can gain insights into its functions, regulatory mechanisms, and potential contributions to various cellular processes, contributing to a deeper understanding of the molecular processes involving UTP11L and its significance in cellular biology. Overall, UTP11L Activators provide valuable tools for exploring the functions and regulatory mechanisms of this gene and protein in the context of cellular physiology and molecular biology research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid regulates cell differentiation and growth, potentially influencing UTP11L expression as part of its broad effects on gene regulation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D inhibits RNA polymerase, affecting rRNA synthesis and potentially upregulating UTP11L as a compensatory mechanism to maintain ribosome biogenesis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator of cell growth and protein synthesis, potentially affecting UTP11L expression in response to altered ribosome biogenesis. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As an HDAC inhibitor, Trichostatin A could enhance UTP11L transcription by increasing histone acetylation and improving chromatin accessibility. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor might lead to DNA demethylation, potentially activating UTP11L expression through epigenetic modifications. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $105.00 $408.00 $1224.00 | 35 | |
Leptomycin B, an inhibitor of nuclear export, could lead to the accumulation of rRNA processing factors like UTP11L in the nucleus, indirectly affecting its expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea causes DNA damage and replication stress, potentially inducing UTP11L expression as part of the cellular response to maintain ribosome biogenesis under stress. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises cAMP levels, which could modulate UTP11L expression through cAMP-dependent signaling pathways involved in cell growth and proliferation. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, affecting purine synthesis and potentially influencing UTP11L expression due to altered nucleotide availability. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin induces ER stress by disrupting calcium homeostasis, potentially upregulating UTP11L as part of the unfolded protein response to maintain protein synthesis. | ||||||