Date published: 2026-2-14

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USP17L2 Activators

Ubiquitin-Specific Protease 17-Like Family Member 2 (USP17L2), usually abbreviated as USP17L2, is a protein encoded by the USP17L2 gene in humans. It's a member of the ubiquitin-specific protease (USP) family, a large group of proteins that play vital roles in protein degradation, regulation, and signaling.USP17L2, like other USPs, functions as a deubiquitinating enzyme (DUB). DUBs are responsible for removing ubiquitin molecules from proteins. The ubiquitin-proteasome system is a critical pathway for protein degradation in cells, functioning as a regulatory mechanism for numerous cellular processes, including cell cycle, DNA repair, and signal transduction.

The specific action of USP17L2 in the deubiquitination process contributes to the regulation of protein turnover and function, impacting cell growth and survival. It's also involved in modulating the activity of other proteins, influencing their stability, localization, and interactions. Research has suggested a link of USP17L2 and other USP17 family members to inflammatory diseases and cancer due to their role in cell growth and division. Dysregulation of deubiquitinating enzymes can lead to unchecked cellular proliferation, a hallmark of many cancers.In summary, USP17L2 is a protein with significant implications in various cellular processes and diseases.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol has been shown to upregulate the expression of various genes. It may potentially enhance the expression of USP17L2 through its ability to modulate gene transcription.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has been reported to possess anti-inflammatory and antioxidant properties . It may contribute to the induction of USP17L2 expression through its regulatory effects on gene expression.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid with antioxidant and anti-inflammatory properties . It may potentially increase USP17L2 expression by modulating gene regulatory mechanisms.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein is an isoflavone found in soybeans with potential anticancer properties . It may participate in the induction of USP17L2 expression through its effects on gene transcription.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane is a compound found in cruciferous vegetables with potential anticancer properties . It may contribute to the upregulation of USP17L2 expression through its effects on gene regulation.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a catechin found in green tea with antioxidant and anticancer properties . It may potentially increase USP17L2 expression through its modulation of gene transcription.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties . It may enhance the expression of USP17L2 through its effects on gene regulation.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid is a derivative of vitamin A with various biological functions . It may contribute to the induction of USP17L2 expression through its regulatory effects on gene transcription.

Troglitazone

97322-87-7sc-200904
sc-200904B
sc-200904A
5 mg
10 mg
25 mg
$110.00
$204.00
$435.00
9
(1)

Troglitazone is an antidiabetic agent in research with potential anti-inflammatory effects . It may potentially increase USP17L2 expression through its modulation of gene regulatory mechanisms.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

1,25-Dihydroxyvitamin D3 is the active form of vitamin D with various physiological functions . It may participate in the upregulation of USP17L2 expression through its effects on gene transcription.