Ubiquitin-Specific Protease 17-Like Family Member 2 (USP17L2), usually abbreviated as USP17L2, is a protein encoded by the USP17L2 gene in humans. It's a member of the ubiquitin-specific protease (USP) family, a large group of proteins that play vital roles in protein degradation, regulation, and signaling.USP17L2, like other USPs, functions as a deubiquitinating enzyme (DUB). DUBs are responsible for removing ubiquitin molecules from proteins. The ubiquitin-proteasome system is a critical pathway for protein degradation in cells, functioning as a regulatory mechanism for numerous cellular processes, including cell cycle, DNA repair, and signal transduction.
The specific action of USP17L2 in the deubiquitination process contributes to the regulation of protein turnover and function, impacting cell growth and survival. It's also involved in modulating the activity of other proteins, influencing their stability, localization, and interactions. Research has suggested a link of USP17L2 and other USP17 family members to inflammatory diseases and cancer due to their role in cell growth and division. Dysregulation of deubiquitinating enzymes can lead to unchecked cellular proliferation, a hallmark of many cancers.In summary, USP17L2 is a protein with significant implications in various cellular processes and diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to upregulate the expression of various genes. It may potentially enhance the expression of USP17L2 through its ability to modulate gene transcription. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been reported to possess anti-inflammatory and antioxidant properties . It may contribute to the induction of USP17L2 expression through its regulatory effects on gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with antioxidant and anti-inflammatory properties . It may potentially increase USP17L2 expression by modulating gene regulatory mechanisms. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is an isoflavone found in soybeans with potential anticancer properties . It may participate in the induction of USP17L2 expression through its effects on gene transcription. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables with potential anticancer properties . It may contribute to the upregulation of USP17L2 expression through its effects on gene regulation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a catechin found in green tea with antioxidant and anticancer properties . It may potentially increase USP17L2 expression through its modulation of gene transcription. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties . It may enhance the expression of USP17L2 through its effects on gene regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a derivative of vitamin A with various biological functions . It may contribute to the induction of USP17L2 expression through its regulatory effects on gene transcription. | ||||||
Troglitazone | 97322-87-7 | sc-200904 sc-200904B sc-200904A | 5 mg 10 mg 25 mg | $110.00 $204.00 $435.00 | 9 | |
Troglitazone is an antidiabetic agent in research with potential anti-inflammatory effects . It may potentially increase USP17L2 expression through its modulation of gene regulatory mechanisms. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
1,25-Dihydroxyvitamin D3 is the active form of vitamin D with various physiological functions . It may participate in the upregulation of USP17L2 expression through its effects on gene transcription. | ||||||