Date published: 2026-5-17

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TTMB Activators

The chemical class known as TTMB Activators encompasses a diverse group of compounds that can modulate the activity of the transmembrane protein TTMB. The underlying methods through which these activators operate are grounded in their ability to influence cellular signaling pathways, each targeting different aspects of cellular communication and regulation. These activators can exert their effect by either upregulating or downregulating enzymes, ion channels, or secondary messenger systems that are indirectly associated with TTMB function within the cell.

Activation of TTMB is understood to be mediated through various signaling cascades, often involving second messengers such as cyclic AMP (cAMP), calcium ions, or lipid-derived molecules like diacylglycerol (DAG). The activators can enhance the production of these messengers or mimic their action, thereby initiating a series of phosphorylation events or conformational changes in proteins that can propagate the signal to TTMB. Moreover, the activators can also lead to the inhibition of phosphatases and kinases that normally act as checkpoints in these signaling pathways. By altering the balance of these enzymes' activities, TTMB activators can modulate the protein's state, influencing its biological activity and its role within the cellular context. The breadth of these signaling mechanisms ensures that TTMB can be modulated in a nuanced manner, allowing fine-tuning of its activity in response to a wide array of cellular stimuli.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Activates adenylyl cyclase, increasing intracellular cAMP levels, which can modulate protein kinase A (PKA) and could activate TMEM200B.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Activates protein kinase C (PKC), which is involved in signal transduction pathways that can influence TTMB's function.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Increases intracellular calcium levels, which can activate calcium-dependent signaling pathways and could activate TTMB.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Inhibits tyrosine kinases and can modulate various signaling pathways that can activate TTMB.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits phosphoinositide 3-kinases (PI3K), and can affect the PI3K/Akt pathway, which can activate TTMB.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$94.00
$227.00
30
(1)

Src family kinase inhibitor, which could modify signaling pathways that can activate TTMB.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase and could affect signaling pathways that can activate TTMB.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibits MEK, which is upstream of ERK in the MAPK pathway, and can activate TTMB.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor that could modify signaling pathways which can activate TTMB.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

mTOR inhibitor that can modulate cell growth and metabolism, and can activate TTMB.