TTC39C Activators
TTC39C activators are a group of chemicals that can influence various biochemical and cellular pathways, resulting in the upregulation or increased activity of the protein TTC39C. This chemical class includes activators of AMPK such as metformin and AICAR, which through the enhancement of cellular energy regulation could lead to modifications in the expression or activity of TTC39C. Activation of the AMPK pathway is well known for its role in metabolic regulation, and since TTC39C has been associated with metabolic processes, compounds that can activate AMPK may, in turn, influence TTC39C activity.
Furthermore, chemicals like rosiglitazone and pioglitazone, which are PPAR-gamma agonists, and oleoylethanolamide, a PPAR-alpha activator, have the capacity to modify transcriptional programs within the cell. Their role in the regulation of genes associated with metabolism suggests a possible connection to TTC39C expression or activity. Compounds such as SRT1720 and resveratrol, through the activation of SIRT1, can impact the deacetylation status of transcription factors and histones, thereby influencing gene expression patterns that could include TTC39C.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin activates AMP-activated protein kinase (AMPK), which is involved in cellular energy homeostasis. Activation of AMPK can lead to transcriptional changes and may enhance the expression or function of TTC39C if it is part of AMPK's downstream regulatory network. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is an AMPK agonist that mimics the effects of AMP; thus, it can activate AMPK, potentially influencing transcription and potentially increasing the expression of TTC39C if it is under the control of AMPK-responsive elements. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone is a PPAR-gamma agonist, which can lead to altered transcription of genes involved in glucose and lipid metabolism. If TTC39C is a PPAR-gamma responsive gene, this could result in increased TTC39C activity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone, another PPAR-gamma agonist, similar to Rosiglitazone, can modulate transcription affecting genes involved in metabolic pathways. An increase in TTC39C activity could be possible if it is responsive to PPAR-gamma activation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin stimulates the production of cAMP, which in turn can activate PKA, leading to phosphorylation of various transcription factors. This pathway may upregulate the expression of TTC39C if it falls under these transcription factors' regulatory influence. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid engages nuclear receptors and modulates gene expression. TTC39C could be influenced if it is part of the retinoid-responsive gene set. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $197.00 $364.00 | 13 | |
SRT1720 is an activator of SIRT1, a member of the sirtuin family of NAD+-dependent deacetylases involved in aging and metabolic regulation. SIRT1 activation can lead to the deacetylation and modification of transcription factors, which could increase the expression of TTC39C if it is regulated by such factors. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate various signaling pathways, including those involved in inflammation and oxidative stress. If TTC39C expression is sensitive to changes in these pathways, curcumin could modulate its activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to activate SIRT1 and has been shown to influence energy homeostasis and metabolism. Through the activation of SIRT1, resveratrol can potentially increase the expression or activity of TTC39C if linked to the SIRT1 signaling axis. | ||||||
Oleylethanolamide | 111-58-0 | sc-201400 sc-201400A | 10 mg 50 mg | $90.00 $194.00 | 1 | |
Oleoylethanolamide can activate PPAR-alpha, which modulates lipid metabolism and inflammation. If TTC39C is involved in lipid regulatory pathways governed by PPAR-alpha, this compound could increase the expression or activity of TTC39C. | ||||||