TSGA2 Activators
TSGA10 activators are compounds that potentially regulate the activity of TSGA10 indirectly through various cellular mechanisms and signaling pathways. These activators may include small molecules that modulate gene expression, protein synthesis, and post-translational modifications. Some of these chemicals, such as epigallocatechin gallate and retinoic acid, exert their effects through antioxidant response pathways or through specific receptor-mediated gene regulation, respectively, which can lead to an increased expression or functional activity of TSGA10. Others, like forskolin and 5-azacytidine, act by elevating intracellular second messengers or modifying epigenetic marks, which can also affect the levels and functionality of TSGA10 in cells.
Further, chemicals such as trichostatin A and sodium butyrate are known to alter chromatin structure and gene expression patterns by inhibiting histone deacetylases, potentially leading to the upregulation of TSGA10. The impact of metal ions, like those provided by ZnSO4, on the protein assembly and function, as well as the influence of vitamin derivatives like ascorbic acid and nicotinamide on post-translational modifications and metabolism, reflects the multifaceted nature of cellular regulation that can be harnessed to indirectly modulate the activity of proteins such as TSGA10.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a catechin found in green tea that can modulate cellular antioxidant pathways. It may enhance the expression of a broad range of proteins, including potentially TSGA10, by activating NRF2 signaling. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, leading to an increase in cAMP levels. Elevated cAMP can enhance protein kinase A (PKA) activity, which may subsequently phosphorylate and modulate proteins associated with ciliary function, possibly including TSGA10. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor. By causing DNA hypomethylation, it can upregulate the expression of genes, which could include TSGA10. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA is a histone deacetylase inhibitor, which can lead to hyperacetylation of histones and activation of gene transcription, potentially affecting TSGA10 expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can regulate gene expression via retinoic acid receptors. It plays a role in cell differentiation and may influence the expression of proteins like TSGA10 during spermatogenesis. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc sulfate can influence cellular metal ion balance and has been associated with the regulation of gene expression and protein assembly, which may impact TSGA10 function in sperm development. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, a short-chain fatty acid, acts as a histone deacetylase inhibitor, potentially leading to increased expression of genes including those related to ciliary function like TSGA10. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences the Wnt signaling pathway. While it's known to inhibit GSK-3β indirectly, leading to increased beta-catenin levels, it might also affect the expression of proteins associated with the cytoskeleton and ciliary function. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Ascorbic acid (Vitamin C) is an essential nutrient that can act as a cofactor for hydroxylases, which are involved in the post-translational modification of ciliary proteins, possibly including TSGA10. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide is a form of vitamin B3 and acts as a precursor for NAD+. It can modulate cellular metabolism and has been shown to influence protein expression and longevity, potentially affecting TSGA10. | ||||||