TSGA2 Inhibitors
TSGA2 inhibitors represent a diverse class of chemicals unified by their potential impact on ciliary function, assembly, and dynamics, which are processes TSGA2 is intrinsically associated with. Cilia, as cellular antennae, are heavily reliant on the precise orchestration of actin and microtubule dynamics. Agents like Cytochalasin D and Latrunculin A target actin structures, with the former disrupting filaments and the latter impeding their polymerization. This can affect ciliary assembly, providing a means to indirectly influence TSGA2.
Microtubules, the structural core of cilia, are the targets of Nocodazole and Fenbendazole, which disrupt their assembly, while Taxol stabilizes them. This modulation of microtubule dynamics offers another approach to potentially affect TSGA2 function. Targeting the motor proteins and energy processes of cilia, Ciliobrevin D and EHNA act on dynein, a vital protein in ciliary movement, and Oligomycin A limits ATP production, crucial for ciliary dynamics.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Acts by disrupting actin filaments, which can affect ciliary assembly and function, thereby influencing TSGA2 indirectly. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Binds actin monomers preventing polymerization, which may disrupt ciliary assembly, potentially affecting TSGA2 activity. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Microtubule-disrupting agent which can affect ciliary structure and function, possibly impacting TSGA2 indirectly. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules which can have effects on ciliary dynamics, potentially influencing TSGA2. | ||||||
Ciliobrevin D | 1370554-01-0 | sc-507482 | 10 mg | $413.00 | ||
Specifically targets cytoplasmic dynein, affecting cilia-related processes, which might impact TSGA2 indirectly. | ||||||
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
Though known as a lipase inhibitor, it has shown inhibition of ciliogenesis, potentially affecting TSGA2. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $146.00 $12250.00 | 18 | |
Inhibits ATP synthase in mitochondria, can influence cellular energy affecting ciliary dynamics, potentially impacting TSGA2. | ||||||
Trichloroacetaldehyde-13C2 | sc-474862 | 2.5 mg | $380.00 | |||
Can alter ciliary beat frequency which can provide an indirect influence on TSGA2. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Affects microtubule function, potentially influencing ciliary dynamics and TSGA2 function. | ||||||