Tsc-22 D4 inhibitors are a class of chemical compounds that target and modulate the activity of the Tsc-22 D4 protein. Tsc-22 D4, also known as transforming growth factor β-stimulated clone 22 domain family member 4, is a transcription factor that plays a critical role in regulating gene expression and cell signaling pathways. It belongs to the Tsc-22 family of proteins, which are involved in various cellular processes, including cell growth, differentiation, and apoptosis. Tsc-22 D4, in particular, is implicated in the regulation of immune responses, inflammation, and cell cycle control.
Chemically, Tsc-22 D4 inhibitors are designed to interact with the protein's active site or binding pockets, thereby altering its function. These inhibitors can be small molecules or peptides specifically tailored to disrupt the protein-protein interactions or DNA-binding activity of Tsc-22 D4. By doing so, they can modulate downstream cellular processes and signaling pathways controlled by Tsc-22 D4. Understanding the mechanisms by which Tsc-22 D4 inhibitors function at the molecular level is crucial for unraveling their implications in various biological contexts. Researchers are actively investigating the precise modes of action and exploring the potential of these inhibitors, but it's important to note that their applications and implications extend beyond the scope of this description.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
As a DNA methyltransferase inhibitor, it may demethylate promoter regions, potentially leading to altered expression of genes including TSC-22D4. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
By inhibiting histone deacetylases, TSA can change the chromatin structure, potentially impacting the transcription of genes such as TSC-22D4. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
As an HDAC inhibitor, it could influence gene expression patterns, possibly affecting TSC-22D4. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Known to inhibit mTOR, which could influence protein synthesis and degradation pathways, potentially impacting TSC-22D4 levels. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
As a proteasome inhibitor, it could influence the degradation of proteins, potentially stabilizing negative regulators of TSC-22D4, leading to its decreased expression. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $66.00 $153.00 | 16 | |
An HSP90 inhibitor, potentially influencing the stability and function of proteins involved in regulating TSC-22D4. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Known to intercalate into DNA and inhibit RNA polymerase, potentially decreasing the transcription of TSC-22D4. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A kinase inhibitor that might influence signaling pathways regulating TSC-22D4 expression. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Another kinase inhibitor that could impact signaling pathways, possibly altering TSC-22D4 expression. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
By inhibiting lysosomal activity, it could impact protein degradation and potentially influence TSC-22D4 levels. | ||||||