TRAP95 inhibitors represent a distinctive class of chemical compounds that target the TRAP95 protein, also known as Tat-activating regulatory protein of 95 kDa. TRAP95 is a multifunctional protein involved in various cellular processes, particularly in the regulation of transcriptional activities. This protein plays a pivotal role in the assembly of the p400/Tip60 chromatin remodeling complex, which, in turn, modulates the acetylation of histones and contributes to the dynamic regulation of gene expression. The development of TRAP95 inhibitors stems from the recognition of the crucial role this protein plays in cellular functions, particularly in the context of chromatin remodeling.
The chemical structures of TRAP95 inhibitors are designed to interact specifically with the catalytic sites or binding domains of TRAP95, hindering its enzymatic activity or disrupting its interactions with other cellular components. By selectively inhibiting TRAP95, these compounds aim to modulate the intricate network of molecular events governing transcriptional regulation. Researchers are actively exploring the applications of TRAP95 inhibitors in unraveling the complexities of gene expression and understanding the underlying mechanisms of various cellular processes.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A kinase inhibitor that can affect various signaling pathways, potentially altering TRAP95 function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can disrupt downstream signaling, potentially affecting TRAP95 interaction. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that might modify cytoskeletal dynamics, indirectly impacting TRAP95. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can alter cellular growth pathways, potentially affecting TRAP95 levels. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis, which can lead to a decrease in TRAP95 expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor that can disrupt cell survival signaling, potentially affecting TRAP95. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which can alter stress response pathways, potentially impacting TRAP95. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
An ER stress inducer that can lead to signaling changes, potentially influencing TRAP95 levels. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport, which can affect TRAP95's role in the cytoskeleton. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An ERK pathway inhibitor that might modulate signaling pathways involving TRAP95. |