TRAP-γ Inhibitors
TRAP-γ inhibitors consist of a diverse collection of chemicals that function by targeting a multitude of signaling pathways. These pathways may be associated with TRAP-γ's biological role. Staurosporine, as a broad-spectrum kinase inhibitor, offers utility in curtailing diverse kinase-dependent processes, possibly linked to TRAP-γ. Chemicals like LY294002 and Wortmannin, both PI3K inhibitors, provide insights into the involvement of TRAP-γ within the phosphoinositide 3-kinase pathway.
PD98059, SP600125, and SB203580 inhibit the ERK, JNK, and p38 MAPK pathways respectively. The presence of these inhibitors suggests a conjecture about TRAP-γ's integration within these pathways. BAPTA and KN-93 bring attention to calcium-based cellular mechanisms that TRAP-γ may interact with, emphasizing calcium as a regulatory ion. U73122 focuses on lipid signaling, offering a perspective on TRAP-γ's possible operation in phospholipase C related processes. Finally, Y-27632 and Genistein offer a view on TRAP-γ's interplay within ROCK and tyrosine kinase pathways.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Broad-spectrum kinase inhibitor; can influence a range of signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor; if TRAP-γ is involved in PI3K signaling, LY294002 can inhibit its activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
ERK pathway inhibitor; can inhibit TRAP-γ if it operates within the ERK pathway. | ||||||
BAPTA, Free Acid | 85233-19-8 | sc-201508 sc-201508A | 100 mg 500 mg | $67.00 $262.00 | 10 | |
Calcium chelator; if TRAP-γ functions are calcium-dependent, BAPTA can inhibit its activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor; can inhibit TRAP-γ if it has roles in mTOR signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor; can inhibit TRAP-γ if it functions within the JNK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor; can inhibit TRAP-γ if it's associated with the p38 MAPK pathway. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
CaMKII inhibitor; can inhibit TRAP-γ if its functions are modulated by CaMKII. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor; can influence TRAP-γ if it's part of PI3K signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
ROCK inhibitor; can inhibit TRAP-γ if it's involved in the ROCK pathway. | ||||||