TRAP-1 Activators
Chemicals classified as TRAP-1 Activators encompass a diverse array of compounds that indirectly influence the activity of Transforming growth factor-beta receptor-associated protein 1 (TRAP-1). These compounds primarily function by modulating mitochondrial metabolism or apoptosis pathways, both of which are crucial to the functional role of TRAP-1, especially in the context of cancer biology.
Compounds like Metformin, Resveratrol, and Coenzyme Q10 affect mitochondrial metabolism by either enhancing or inhibiting key aspects of mitochondrial function. By altering mitochondrial dynamics, these compounds can indirectly influence TRAP-1, which is known to play a role in mitochondrial metabolism. Other compounds, such as Rotenone, Oligomycin, Antimycin A, Cyanide, and Sodium Azide, target specific components of the mitochondrial electron transport chain, leading to changes in mitochondrial function and affecting TRAP-1 activity. Furthermore, compounds like Tamoxifen and Vitamin E modulate apoptotic pathways. Tamoxifen, known for its anti-estrogenic properties, also influences apoptosis, a process in which TRAP-1 is implicated. Vitamin E, as an antioxidant, can affect oxidative stress levels in cells, thereby influencing apoptosis and impacting TRAP-1 activity.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Influences mitochondrial metabolism, potentially affecting TRAP-1 activity by modulating mitochondrial functions. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Affects mitochondrial biogenesis and function, potentially impacting TRAP-1 activity through alterations in mitochondrial dynamics. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
As a mitochondrial complex I inhibitor, it can influence mitochondrial metabolism, potentially affecting TRAP-1 activity. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Inhibits mitochondrial ATP synthase, altering mitochondrial function and potentially influencing TRAP-1 activity. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Inhibits mitochondrial complex III, affecting mitochondrial metabolism which could indirectly impact TRAP-1. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Known for its role in modulating apoptosis, it could indirectly influence TRAP-1 activity. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B sc-214454C | 10 g 25 g 100 g 1 kg | $43.00 $62.00 $141.00 $430.00 | ||
As an antioxidant, it affects oxidative stress and mitochondrial function, potentially impacting TRAP-1 activity. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Involved in mitochondrial electron transport, it could influence mitochondrial metabolism and indirectly affect TRAP-1. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
A precursor in NAD+ biosynthesis, influences mitochondrial metabolism, potentially impacting TRAP-1. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Inhibits glycolysis and affects energy metabolism, potentially influencing mitochondrial function and TRAP-1 activity. | ||||||