Date published: 2026-2-22

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TPPII Activators

TPPII (Tripeptidyl peptidase II) activators represent a category of chemical compounds that have the potential to influence TPPII activity indirectly within the cellular context. TPPII is an enzyme with a significant role in proteolysis and protein processing within cells.

TPPII activators encompass a variety of compounds, including proteasome inhibitors like MG-132, Lactacystin, and Bortezomib, which can alter proteasomal degradation pathways, potentially affecting TPPII within the cellular proteostasis network. Cysteine protease inhibitors such as E-64 and serine protease inhibitors like Aprotinin may indirectly influence TPPII by modulating proteolytic processes. Additionally, compounds like Calpain Inhibitor I and ALLN, which target various proteolytic pathways, can potentially impact TPPII indirectly. Autophagy inhibitors like 3-Methyladenine, while not directly acting on TPPII, may intersect with proteolytic pathways that influence TPPII activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Proteasome inhibitor that can potentially influence TPPII activity by altering proteasomal degradation pathways, indirectly impacting cellular proteostasis.

E-64

66701-25-5sc-201276
sc-201276A
sc-201276B
5 mg
25 mg
250 mg
$281.00
$947.00
$1574.00
14
(0)

Cysteine protease inhibitor that may indirectly affect TPPII by modulating proteolytic processes within the cell.

MG-115

133407-86-0sc-221940
sc-221940A
1 mg
5 mg
$89.00
$224.00
3
(1)

Proteasome inhibitor that can alter protein degradation pathways, potentially influencing TPPII within the cellular proteostasis network.

Chymostatin

9076-44-2sc-202541
sc-202541A
sc-202541B
sc-202541C
sc-202541D
5 mg
10 mg
25 mg
50 mg
100 mg
$156.00
$260.00
$640.00
$1186.00
$2270.00
3
(1)

Chymostatin is a chymotrypsin-like protease inhibitor that may indirectly affect TPPII by modulating proteolytic processes within the cell.

α-Iodoacetamide

144-48-9sc-203320
25 g
$255.00
1
(1)

Iodoacetamide is an alkylating agent that can potentially modulate proteolytic pathways, indirectly influencing TPPII activity.

Autophagy Inhibitor, 3-MA

5142-23-4sc-205596
sc-205596A
50 mg
500 mg
$65.00
$261.00
113
(3)

3-Methyladenine is an autophagy inhibitor that may indirectly affect TPPII by altering autophagic processes that intersect with proteolytic pathways.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Proteasome inhibitor that can influence proteasomal degradation pathways, potentially impacting TPPII within the cellular proteostasis network.

Aprotinin

9087-70-1sc-3595
sc-3595A
sc-3595B
10 mg
100 mg
1 g
$112.00
$408.00
$3000.00
51
(2)

Aprotinin is a serine protease inhibitor that can affect various proteolytic processes, potentially influencing TPPII indirectly.