TPPII (Tripeptidyl peptidase II) activators represent a category of chemical compounds that have the potential to influence TPPII activity indirectly within the cellular context. TPPII is an enzyme with a significant role in proteolysis and protein processing within cells.
TPPII activators encompass a variety of compounds, including proteasome inhibitors like MG-132, Lactacystin, and Bortezomib, which can alter proteasomal degradation pathways, potentially affecting TPPII within the cellular proteostasis network. Cysteine protease inhibitors such as E-64 and serine protease inhibitors like Aprotinin may indirectly influence TPPII by modulating proteolytic processes. Additionally, compounds like Calpain Inhibitor I and ALLN, which target various proteolytic pathways, can potentially impact TPPII indirectly. Autophagy inhibitors like 3-Methyladenine, while not directly acting on TPPII, may intersect with proteolytic pathways that influence TPPII activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can potentially influence TPPII activity by altering proteasomal degradation pathways, indirectly impacting cellular proteostasis. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
Cysteine protease inhibitor that may indirectly affect TPPII by modulating proteolytic processes within the cell. | ||||||
MG-115 | 133407-86-0 | sc-221940 sc-221940A | 1 mg 5 mg | $89.00 $224.00 | 3 | |
Proteasome inhibitor that can alter protein degradation pathways, potentially influencing TPPII within the cellular proteostasis network. | ||||||
Chymostatin | 9076-44-2 | sc-202541 sc-202541A sc-202541B sc-202541C sc-202541D | 5 mg 10 mg 25 mg 50 mg 100 mg | $156.00 $260.00 $640.00 $1186.00 $2270.00 | 3 | |
Chymostatin is a chymotrypsin-like protease inhibitor that may indirectly affect TPPII by modulating proteolytic processes within the cell. | ||||||
α-Iodoacetamide | 144-48-9 | sc-203320 | 25 g | $255.00 | 1 | |
Iodoacetamide is an alkylating agent that can potentially modulate proteolytic pathways, indirectly influencing TPPII activity. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $65.00 $261.00 | 113 | |
3-Methyladenine is an autophagy inhibitor that may indirectly affect TPPII by altering autophagic processes that intersect with proteolytic pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor that can influence proteasomal degradation pathways, potentially impacting TPPII within the cellular proteostasis network. | ||||||
Aprotinin | 9087-70-1 | sc-3595 sc-3595A sc-3595B | 10 mg 100 mg 1 g | $112.00 $408.00 $3000.00 | 51 | |
Aprotinin is a serine protease inhibitor that can affect various proteolytic processes, potentially influencing TPPII indirectly. | ||||||