TPPII Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Butabindide oxalate | 185213-03-0 | sc-361130 sc-361130A | 10 mg 50 mg | $189.00 $770.00 | 1 | |
Butabindide oxalate functions as a TPPII, characterized by its capacity to engage in specific electrostatic interactions with active site residues of target proteins. This engagement can lead to conformational changes that modulate enzymatic activity. Its unique steric properties enhance selectivity in binding, while its solubility profile supports effective diffusion across biological membranes. The compound's reactivity as an acid halide further influences its interaction dynamics, shaping the overall biochemical landscape. | ||||||
AAF-CMK | 184901-82-4 | sc-205591 sc-205591A | 5 mg 25 mg | $94.00 $317.00 | 1 | |
AAF-CMK acts as a TPPII, distinguished by its ability to form covalent bonds with serine residues in target enzymes, leading to irreversible inhibition. This compound exhibits a unique reactivity profile as an acid halide, facilitating rapid acylation reactions that alter enzyme functionality. Its hydrophobic characteristics enhance membrane permeability, while specific steric configurations promote selective interactions, ultimately influencing kinetic parameters and reaction pathways in biochemical systems. | ||||||
Cyclo(-Leu-Pro) | 2873-36-1 | sc-285317B sc-285317 sc-285317A sc-285317C | 100 mg 250 mg 1 g 5 g | $124.00 $259.00 $756.00 $2227.00 | ||
Functions similarly to peptide aldehydes and can inactivate TPPII by forming a covalent bond with the active site serine. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $73.00 $148.00 $316.00 $499.00 $1427.00 $101.00 | 19 | |
Leupeptin is a reversible inhibitor that can bind to the active site of TPPII, hindering its enzymatic function. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $137.00 $219.00 $449.00 $506.00 | 19 | |
While primarily an inhibitor of the proteasome, epoxomicin can also inhibit TPPII due to its reactive epoxide group that can interact with the active site threonine. | ||||||
Calpeptin | 117591-20-5 | sc-202516 sc-202516A | 10 mg 50 mg | $121.00 $456.00 | 28 | |
Although a calpain inhibitor, this compound can also inhibit TPPII by obstructing the enzyme's active site. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Lactacystin is known to inhibit the proteasome, but it can also inhibit TPPII by irreversible binding to its active site threonine. | ||||||
(R)-MG-132 | 1211877-36-9 | sc-351846 sc-351846A sc-351846B | 1 mg 5 mg 25 mg | $63.00 $196.00 $843.00 | 9 | |
This tripeptide aldehyde can inhibit TPPII activity by binding to the active site and preventing substrate processing. | ||||||