TMEM91 inhibitors constitute a specialized class of chemical compounds designed to selectively modulate the activity of Transmembrane Protein 91 (TMEM91). Despite being identified as a transmembrane protein, the specific functions and cellular roles of TMEM91 are not well-delineated, as research on this protein is still in its early stages. The inhibitors developed for TMEM91 exhibit a distinct chemical structure that allows them to interact selectively with defined binding sites on the TMEM91 protein, influencing its molecular activities within the cellular context. The precise design of these inhibitors is crucial for ensuring a high degree of specificity, minimizing unintended effects on other cellular components or proteins with similar transmembrane characteristics.
The mechanism of action of TMEM91 inhibitors involves disrupting the normal functioning of the TMEM91 protein, potentially impacting cellular processes associated with its unique role. As researchers explore the complexities of transmembrane proteins and their involvement in cellular functions, TMEM91 inhibitors serve as valuable tools, allowing for the investigation of the precise molecular mechanisms governed by TMEM91. The study of this chemical class contributes to a deeper understanding of the role played by TMEM91 in cellular physiology, offering insights into its potential functions within the intricate networks that govern cellular membranes and transmembrane signaling. Overall, the exploration of TMEM91 inhibitors provides a platform for advancing our understanding of the molecular landscape surrounding this relatively less-explored transmembrane protein and its implications in cellular processes.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
This compound inhibits eukaryotic protein synthesis by interfering with the translocation step in protein elongation. While it does not inhibit mRNA synthesis directly, reduced translation can sometimes lead to decreased mRNA stability. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin causes premature chain termination during translation by acting as an analog of aminoacyl-tRNA, which can lead to reduced protein levels, potentially affecting TMEM91 indirectly. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D binds to DNA and inhibits RNA polymerase action, which would suppress the transcription of most genes, including TMEM91. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
A topoisomerase I inhibitor that can interfere with DNA replication and transcription processes, potentially reducing the expression of TMEM91. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB is an adenosine analog that inhibits RNA polymerase II, thus could decrease the transcription of TMEM91. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A potent inhibitor of RNA polymerase II derived from the death cap mushroom (Amanita phalloides), which could suppress TMEM91 transcription. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
An inhibitor of inosine monophosphate dehydrogenase that can deplete guanosine nucleotides, potentially affecting RNA synthesis and reducing TMEM91 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
A flavonoid with antioxidant properties that has been shown to modulate various signaling pathways and could potentially alter gene expression profiles, including TMEM91. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A specific inhibitor of mitogen-activated protein kinase kinase (MEK), which could alter the expression of genes regulated by the MAPK/ERK pathway, potentially impacting TMEM91 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific inhibitor of phosphoinositide 3-kinases (PI3K), which might affect the PI3K/AKT signaling pathway and subsequently influence the expression of certain genes, including TMEM91. | ||||||