TMEM44 Activators
TMEM44 activators represent a specialized class of chemical compounds designed to modulate the activity of the TMEM44 gene, which encodes the transmembrane protein 44. This gene is categorized as an open reading frame (ORF) in the human genome, and the specific biological functions and cellular roles of the TMEM44 protein are currently not well characterized. Activators of TMEM44 have been developed to investigate the potential involvement of this protein in various cellular processes, including signaling pathways, protein-protein interactions, or other essential biological functions. By enhancing the activity or influencing the interactions of the TMEM44 protein, these compounds provide a valuable tool for exploring its functions and contribute to the broader understanding of gene function within the human genome.
The study of TMEM44 activators requires a multidisciplinary approach, encompassing principles from synthetic chemistry, molecular biology, and cell biology. To develop these compounds, researchers need a comprehensive understanding of the TMEM44 protein, including its structural domains and potential interaction partners within the cellular context. The identification of molecules capable of specifically enhancing the activity or interactions of TMEM44 involves screening chemical libraries for compounds that can bind to the protein or modulate its function. This research includes in vitro assays to assess changes in protein activity or interactions, as well as cellular studies to observe the effects of TMEM44 activation on broader physiological processes. Techniques such as mass spectrometry for protein-protein interaction analysis, fluorescence microscopy for cellular localization studies, and functional assays to evaluate cellular responses may be employed to elucidate the functional consequences of activating TMEM44. Through these comprehensive investigations, researchers aim to unravel the biological significance of TMEM44 and its potential role in cellular processes, contributing to the ongoing exploration of gene function within the human genome.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $385.00 $2654.00 | ||
Vitamin A, through its metabolite retinoic acid, binds to retinoid receptors affecting gene transcription in cells with these receptors. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A catechin found in green tea that may modulate signaling pathways and alter gene expression profiles. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
A flavonoid that may influence gene expression by modulating signaling pathways and acting as an antioxidant. | ||||||
Piperlongumine | 20069-09-4 | sc-364128 | 10 mg | $107.00 | ||
A bioactive compound from the Piper longum fruit that may affect cellular stress pathways and gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A plant flavonol from the flavonoid group of polyphenols that may modulate gene expression through antioxidant effects. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
An isothiocyanate present in cruciferous vegetables that may alter gene expression via the NRF2 signaling pathway. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
A compound that inhibits N-linked glycosylation, potentially affecting protein folding and expression levels. | ||||||
Vinclozolin | 50471-44-8 | sc-251425 | 250 mg | $23.00 | 1 | |
A fungicide that may act as an endocrine disruptor, potentially influencing gene expression through hormone signaling pathways. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
A potent inhibitor of tyrosine phosphatases, possibly altering phosphorylation-dependent signaling pathways and gene expression. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
An organic synthetic compound that may interact with estrogen receptors, potentially affecting gene expression. | ||||||