Date published: 2025-10-11

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TMEM37 Inhibitors

TMEM37 inhibitors belong to a specific chemical class renowned for their capacity to modulate the activity of transmembrane protein 37 (TMEM37), a protein integral to cellular processes. Transmembrane proteins play pivotal roles in facilitating the transport of substances across cell membranes, mediating signal transduction, and maintaining cellular integrity. TMEM37 itself is a transmembrane protein whose precise physiological functions are still under investigation. In recent years, researchers have identified and developed a class of chemical compounds recognized as TMEM37 inhibitors, designed to interact selectively with the TMEM37 protein, thereby altering its activity.

TMEM37 inhibitors are characterized by distinctive features that confer their inhibitory properties. These compounds typically possess functional groups and molecular motifs essential for specific interactions with the TMEM37 protein, disrupting its normal cellular functions. The development of TMEM37 inhibitors has garnered attention within the scientific community due to the potential implications for understanding cellular processes and unraveling the biological significance of the TMEM37 protein. Further research is essential to elucidate the intricate mechanisms of TMEM37 inhibition and its consequences on cellular pathways, paving the way for a more comprehensive understanding of this chemical class and its impact on cellular function.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Verapamil

52-53-9sc-507373
1 g
$367.00
(0)

Calcium channel blocker that can alter the function of transmembrane proteins by changing ion gradients.

Propranolol

525-66-6sc-507425
100 mg
$180.00
(0)

Beta-blocker that can interfere with signaling pathways involving transmembrane receptors.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Tyrosine kinase inhibitor that can modulate signal transduction involving transmembrane proteins.

Amiloride

2609-46-3sc-337527
1 g
$290.00
7
(1)

Sodium channel inhibitor that can affect transmembrane potential and related functions.

Omeprazole

73590-58-6sc-202265
50 mg
$66.00
4
(1)

Proton pump inhibitor that can indirectly affect the environment of transmembrane proteins by altering pH.

Losartan

114798-26-4sc-353662
100 mg
$127.00
18
(1)

Angiotensin II receptor antagonist that can influence signaling pathways in cells.

Itraconazole

84625-61-6sc-205724
sc-205724A
50 mg
100 mg
$76.00
$139.00
23
(1)

Inhibits cytochrome P450 enzymes which can have downstream effects on transmembrane proteins.

Diltiazem

42399-41-7sc-204726
sc-204726A
1 g
5 g
$209.00
$464.00
4
(1)

Another calcium channel blocker that can change transmembrane ion dynamics.

Tamoxifen

10540-29-1sc-208414
2.5 g
$256.00
18
(2)

Modulates the activity of estrogen receptors which can influence transmembrane protein signaling.

Chlorpromazine

50-53-3sc-357313
sc-357313A
5 g
25 g
$60.00
$108.00
21
(1)

Blocks dopamine and other receptors which can indirectly affect transmembrane proteins.