Tmem210 Inhibitors
The theoretical class of TMEM210 Inhibitors would consist of molecules that can indirectly influence the function of the TMEM210 protein through modulation of cellular processes, membrane dynamics, and signaling pathways. For instance, Cyclosporin A and Genistein can modulate the phosphorylation state of proteins, potentially altering TMEM210 or its interacting partners. Compounds like Cholesterol, Filipin, and GW4869 can alter the lipid environment of the cellular membrane where TMEM210 is embedded, potentially affecting its conformation and activity.
Further, compounds such as Dynasore and Brefeldin A disrupt the trafficking and endocytosis of membrane proteins, which can indirectly influence the localization and density of TMEM210 at the cellular membrane. Amiloride and Monensin can alter ion gradients and transport mechanisms, which are crucial for the maintenance of cellular homeostasis and can also impact transmembrane protein function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Inhibits calcineurin, potentially altering transmembrane protein phosphorylation and function. | ||||||
Cholesterol | 57-88-5 | sc-202539C sc-202539E sc-202539A sc-202539B sc-202539D sc-202539 | 5 g 5 kg 100 g 250 g 1 kg 25 g | $26.00 $2754.00 $126.00 $206.00 $572.00 $86.00 | 11 | |
Modulates membrane fluidity and can affect transmembrane protein conformation and signaling. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Tyrosine kinase inhibitor that can affect protein function by altering phosphorylation states. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Inhibits dynamin, potentially affecting the endocytosis and recycling of transmembrane proteins. | ||||||
Filipin III | 480-49-9 | sc-205323 sc-205323A | 500 µg 1 mg | $116.00 $145.00 | 26 | |
Binds to cholesterol, disrupting lipid rafts and potentially affecting transmembrane protein localization. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $56.00 | 6 | |
Inhibits certain ion channels and transporters, potentially altering transmembrane gradients that influence TMEM210. | ||||||
GW4869 | 6823-69-4 | sc-218578 sc-218578A | 5 mg 25 mg | $199.00 $599.00 | 24 | |
Inhibits sphingomyelinase, affecting lipid rafts and membrane microdomains where transmembrane proteins reside. | ||||||
U 18666A | 3039-71-2 | sc-203306 sc-203306A | 10 mg 50 mg | $140.00 $500.00 | 2 | |
Inhibits cholesterol transport, affecting membrane composition and potentially transmembrane protein function. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Affects ion gradients by acting as an ionophore, potentially altering transmembrane signaling. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein trafficking from the ER to the Golgi, possibly affecting transmembrane protein processing. | ||||||